Endothelium and regulatory inflammatory mechanisms during organ rejection

Fabio Silvio Taccone; Ettore Crimi; James Anstey; Teresa Infante; Katia Donadello; Sabino Scolletta; Mohammed Al-Omran; Claudio Napoli

doi:10.1177/0003319713485282

Endothelium and regulatory inflammatory mechanisms during organ rejection

Fabio Silvio Taccone, Ettore Crimi, James Anstey, Teresa Infante, Katia Donadello, Sabino Scolletta, Mohammed Al-Omran, Claudio Napoli

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Abstract

Endothelial integrity is mandatory for physiologic organ function; however, endothelium dysfunction can be caused by systemic inflammation, occurring during sepsis or organ rejection after transplantation. This article will address our current understanding of endothelial involvement in organ transplantation and rejection. Overall, more detailed studies focusing on the endothelial modulation after organ transplantation would be necessary to investigate the role of endothelium activation during organ rejection.

Original language	English
Pages (from-to)	379-387
Number of pages	9
Journal	Angiology
Volume	65
Issue number	5
DOIs	https://doi.org/10.1177/0003319713485282
Publication status	Published - 2014

Keywords

dysfunction
endothelium
inflammation
organ rejection

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1177/0003319713485282

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abstract = "Endothelial integrity is mandatory for physiologic organ function; however, endothelium dysfunction can be caused by systemic inflammation, occurring during sepsis or organ rejection after transplantation. This article will address our current understanding of endothelial involvement in organ transplantation and rejection. Overall, more detailed studies focusing on the endothelial modulation after organ transplantation would be necessary to investigate the role of endothelium activation during organ rejection.",

keywords = "dysfunction, endothelium, inflammation, organ rejection",

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AU - Taccone, Fabio Silvio

AU - Crimi, Ettore

AU - Anstey, James

AU - Infante, Teresa

AU - Donadello, Katia

AU - Scolletta, Sabino

AU - Al-Omran, Mohammed

AU - Napoli, Claudio

PY - 2014

Y1 - 2014

N2 - Endothelial integrity is mandatory for physiologic organ function; however, endothelium dysfunction can be caused by systemic inflammation, occurring during sepsis or organ rejection after transplantation. This article will address our current understanding of endothelial involvement in organ transplantation and rejection. Overall, more detailed studies focusing on the endothelial modulation after organ transplantation would be necessary to investigate the role of endothelium activation during organ rejection.

AB - Endothelial integrity is mandatory for physiologic organ function; however, endothelium dysfunction can be caused by systemic inflammation, occurring during sepsis or organ rejection after transplantation. This article will address our current understanding of endothelial involvement in organ transplantation and rejection. Overall, more detailed studies focusing on the endothelial modulation after organ transplantation would be necessary to investigate the role of endothelium activation during organ rejection.

KW - dysfunction

KW - endothelium

KW - inflammation

KW - organ rejection

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Endothelium and regulatory inflammatory mechanisms during organ rejection

Abstract

Keywords

ASJC Scopus subject areas

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