Endothelium and regulatory inflammatory mechanisms during organ rejection

Fabio Silvio Taccone, Ettore Crimi, James Anstey, Teresa Infante, Katia Donadello, Sabino Scolletta, Mohammed Al-Omran, Claudio Napoli

Research output: Contribution to journalArticlepeer-review

Abstract

Endothelial integrity is mandatory for physiologic organ function; however, endothelium dysfunction can be caused by systemic inflammation, occurring during sepsis or organ rejection after transplantation. This article will address our current understanding of endothelial involvement in organ transplantation and rejection. Overall, more detailed studies focusing on the endothelial modulation after organ transplantation would be necessary to investigate the role of endothelium activation during organ rejection.

Original languageEnglish
Pages (from-to)379-387
Number of pages9
JournalAngiology
Volume65
Issue number5
DOIs
Publication statusPublished - 2014

Keywords

  • dysfunction
  • endothelium
  • inflammation
  • organ rejection

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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