Endovascular Therapy for Infrainguinal Artery Disease with Coronary Devices

Arturo Giordano, Paolo Ferraro, Nicola Corcione, Stefano Messina, Gennaro Maresca, Enrico Coscioni, Raffaella Avellino, Gabriele Giordano, Mariangela Peruzzi, Giuseppe Biondi-Zoccai

Research output: Contribution to journalArticle

Abstract

Several devices are available for infrainguinal endovascular therapy, with drug-eluting stents (DES) among the most promising. Bioresorbable vascular scaffolds (BVS) may further improve outcomes. We have liberally used in our practice coronary DES and BVS for infrainguinal endovascular therapy and hereby report our preliminary results. We conducted an observational study by retrospectively identifying characteristics of patients undergoing infrainguinal implantation of coronary DES or BVS. We compared the risk of major adverse events (MAE: death, amputation, or target vessel revascularization [TVR]) and components of MAE in the overall sample and after propensity matching. We included a total of 204 patients (207 limbs), 148 (72.5%) treated with DES and 56 (27.5%) with BVS. Bivariate analysis showed that TVR was less common in the DES group (41.9% vs 18.4%, P =.014). However, propensity-matched analysis showed nearly identical risks of MAE, amputation, TVR, or symptom burden with DES and BVS (all P >.05). In conclusion, the present pilot experience with coronary BVS suggests that they could provide acceptable results for infrainguinal endovascular procedures, comparable to those obtained by their metallic counterpart.

Original languageEnglish
Pages (from-to)59-66
Number of pages8
JournalAngiology
Volume68
Issue number1
DOIs
Publication statusPublished - Jan 1 2017

Keywords

  • bioresorbable vascular scaffold
  • drug-eluting stent
  • endovascular therapy
  • peripheral artery disease
  • superficial femoral artery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Giordano, A., Ferraro, P., Corcione, N., Messina, S., Maresca, G., Coscioni, E., Avellino, R., Giordano, G., Peruzzi, M., & Biondi-Zoccai, G. (2017). Endovascular Therapy for Infrainguinal Artery Disease with Coronary Devices. Angiology, 68(1), 59-66. https://doi.org/10.1177/0003319716637802