Enhanced in vitro culture of human SAOS-2 osteoblasts on a sand-blasted titanium surface modified with plastic deformation

Lorenzo Fassina, Enrica Saino, Livia Visai, Maria G Cusella De Angelis, Francesco Benazzo, Giovanni Magenes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The titanium surfaces with micro-roughness have been studied to substitute machined titanium, with the focus on enhancing the bone apposition onto the implant. In this study we have followed a biomimetic strategy where human SAOS-2 osteoblasts proliferated and built their extracellular matrix on a sandblasted titanium surface modified with plastic deformation. In comparison with sandblasted titanium surface, the plastic deformation increased the cell proliferation and the surface coating with bone matrix. The superficially modified biomaterial could be used, in clinical applications, as an implant for bone repair.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages6410-6413
Number of pages4
DOIs
Publication statusPublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

ASJC Scopus subject areas

  • Biomedical Engineering

Fingerprint Dive into the research topics of 'Enhanced in vitro culture of human SAOS-2 osteoblasts on a sand-blasted titanium surface modified with plastic deformation'. Together they form a unique fingerprint.

  • Cite this

    Fassina, L., Saino, E., Visai, L., De Angelis, M. G. C., Benazzo, F., & Magenes, G. (2007). Enhanced in vitro culture of human SAOS-2 osteoblasts on a sand-blasted titanium surface modified with plastic deformation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 6410-6413). [4353823] https://doi.org/10.1109/IEMBS.2007.4353823