Enhanced percent age of leu m3+dr+ and leu m3+cd25+ cells in newly diagnosed iddm patients

F. Nicoletti; U. Consoli; D. Calogero; A. M. Speciale; R. Di Marco; C. Leonardo; L. La Rosa; M. Lunetta; A. Di Cataldo; P. L. Meroni

doi:10.3109/08916939109007651

Enhanced percent age of leu m3⁺dr⁺ and leu m3⁺cd25⁺ cells in newly diagnosed iddm patients

F. Nicoletti, U. Consoli, D. Calogero, A. M. Speciale, R. Di Marco, C. Leonardo, L. La Rosa, M. Lunetta, A. Di Cataldo, P. L. Meroni

Fondazione Istituto Auxologico Italiano

Research output: Contribution to journal › Article › peer-review

Abstract

The percentage of Leu M3⁺DR⁺ and of Leu M3⁺CD25⁺ cells was determined by means of immunofluorescence analysis in a group of patients with insulin dependent diabetes mellitus (IDDM). Our results show that an increased percentage of these cells may occur in the early stage of the disease. These data provide evidence for a "phenotypical" activation of Leu M3⁺ cells at the onset of the disease and warrant future studies to evaluate the potential role of these cells in the pathogenesis of IDDM.

Original language	English
Pages (from-to)	255-259
Number of pages	5
Journal	Autoimmunity
Volume	9
Issue number	3
DOIs	https://doi.org/10.3109/08916939109007651
Publication status	Published - 1991

Keywords

Autoimmunity
Cytokines
Insulin-dependent diabetes mellitus

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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abstract = "The percentage of Leu M3+DR+ and of Leu M3+CD25+ cells was determined by means of immunofluorescence analysis in a group of patients with insulin dependent diabetes mellitus (IDDM). Our results show that an increased percentage of these cells may occur in the early stage of the disease. These data provide evidence for a {"}phenotypical{"} activation of Leu M3+ cells at the onset of the disease and warrant future studies to evaluate the potential role of these cells in the pathogenesis of IDDM.",

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T1 - Enhanced percent age of leu m3+dr+ and leu m3+cd25+ cells in newly diagnosed iddm patients

AU - Nicoletti, F.

AU - Consoli, U.

AU - Calogero, D.

AU - Speciale, A. M.

AU - Marco, R. Di

AU - Leonardo, C.

AU - Rosa, L. La

AU - Lunetta, M.

AU - Cataldo, A. Di

AU - Meroni, P. L.

PY - 1991

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KW - Cytokines

KW - Insulin-dependent diabetes mellitus

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