Enhanced pre-ovulatory progesterone levels in fertile cycles during clomiphene citrate treatment

L. Fedele, D. Brioschi, M. Marchini, M. Dorta, A. Baglioni

Research output: Contribution to journalArticlepeer-review

Abstract

We compared ovulatory changes in fertile and preceding infertile cycles in 21 patients with unexplained infertility conceiving after clomiphene citrate treatment. No significant differences were observed in follicular growth, cervical score and follicle stimulating hormone (FSH) levels. Progesterone was higher (P <0.05) in the 2 days preceding ovulation in fertile cycles, luteinizing hormone (LH) higher (P <0.05) the day before, and 17-β-estradiol lower (P <0.05) 4 days before. Stimulating progesterone secretion by systematic LH administration before ovulation could improve secretory endometrial transformation and thus reproductive prognosis.

Original languageEnglish
Pages (from-to)239-242
Number of pages4
JournalInternational Journal of Gynecology and Obstetrics
Volume29
Issue number3
DOIs
Publication statusPublished - 1989

Keywords

  • Clomiphene citrate
  • Conception
  • Endometrium
  • Ovulatory changes
  • Progesterone
  • Unexplained infertility

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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