Enhanced preovulatory progesterone levels in clomiphene citrate-induced cycles

L. Fedele, D. Brioschi, M. Marchini, M. Dorta, F. Parazzini

Research output: Contribution to journalArticlepeer-review


We measured basal body temperature, cervical mucus, follicular diameter, and serum LH, FSH, 17β-estradiol, and progesterone daily in 40 spontaneous ovulatory cycles in 27 infertile women and in 40 clomiphene citrate-induced ovulatory cycles in 31 women. The cervical score was significantly lower and the serum FSH, LH, and 17β-estradiol levels were significantly higher during the follicular phase in induced compared with spontaneous cycles. Serum progesterone was significantly higher on the 3 days preceding ovulation and the day of ovulation in the induced cycles. These increased preovulatory serum progesterone levels could contribute to the lower cervical mucus score in the induced compared with spontaneous cycle, whereas their effect on the endometrium is still unclear.

Original languageEnglish
Pages (from-to)681-683
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Issue number3
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism


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