Enhanced preovulatory progesterone levels in clomiphene citrate-induced cycles

L. Fedele, D. Brioschi, M. Marchini, M. Dorta, F. Parazzini

Research output: Contribution to journalArticle

Abstract

We measured basal body temperature, cervical mucus, follicular diameter, and serum LH, FSH, 17β-estradiol, and progesterone daily in 40 spontaneous ovulatory cycles in 27 infertile women and in 40 clomiphene citrate-induced ovulatory cycles in 31 women. The cervical score was significantly lower and the serum FSH, LH, and 17β-estradiol levels were significantly higher during the follicular phase in induced compared with spontaneous cycles. Serum progesterone was significantly higher on the 3 days preceding ovulation and the day of ovulation in the induced cycles. These increased preovulatory serum progesterone levels could contribute to the lower cervical mucus score in the induced compared with spontaneous cycle, whereas their effect on the endometrium is still unclear.

Original languageEnglish
Pages (from-to)681-683
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume69
Issue number3
Publication statusPublished - 1989

Fingerprint

Clomiphene
Progesterone
Cervix Mucus
Estradiol
Ovulation
Serum
Follicular Phase
Endometrium
Body Temperature
Temperature

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Enhanced preovulatory progesterone levels in clomiphene citrate-induced cycles. / Fedele, L.; Brioschi, D.; Marchini, M.; Dorta, M.; Parazzini, F.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 69, No. 3, 1989, p. 681-683.

Research output: Contribution to journalArticle

@article{f695eaf12eea414097d92ddff5a3d791,
title = "Enhanced preovulatory progesterone levels in clomiphene citrate-induced cycles",
abstract = "We measured basal body temperature, cervical mucus, follicular diameter, and serum LH, FSH, 17β-estradiol, and progesterone daily in 40 spontaneous ovulatory cycles in 27 infertile women and in 40 clomiphene citrate-induced ovulatory cycles in 31 women. The cervical score was significantly lower and the serum FSH, LH, and 17β-estradiol levels were significantly higher during the follicular phase in induced compared with spontaneous cycles. Serum progesterone was significantly higher on the 3 days preceding ovulation and the day of ovulation in the induced cycles. These increased preovulatory serum progesterone levels could contribute to the lower cervical mucus score in the induced compared with spontaneous cycle, whereas their effect on the endometrium is still unclear.",
author = "L. Fedele and D. Brioschi and M. Marchini and M. Dorta and F. Parazzini",
year = "1989",
language = "English",
volume = "69",
pages = "681--683",
journal = "Journal of Clinical Endocrinology and Metabolism",
issn = "0021-972X",
publisher = "The Endocrine Society",
number = "3",

}

TY - JOUR

T1 - Enhanced preovulatory progesterone levels in clomiphene citrate-induced cycles

AU - Fedele, L.

AU - Brioschi, D.

AU - Marchini, M.

AU - Dorta, M.

AU - Parazzini, F.

PY - 1989

Y1 - 1989

N2 - We measured basal body temperature, cervical mucus, follicular diameter, and serum LH, FSH, 17β-estradiol, and progesterone daily in 40 spontaneous ovulatory cycles in 27 infertile women and in 40 clomiphene citrate-induced ovulatory cycles in 31 women. The cervical score was significantly lower and the serum FSH, LH, and 17β-estradiol levels were significantly higher during the follicular phase in induced compared with spontaneous cycles. Serum progesterone was significantly higher on the 3 days preceding ovulation and the day of ovulation in the induced cycles. These increased preovulatory serum progesterone levels could contribute to the lower cervical mucus score in the induced compared with spontaneous cycle, whereas their effect on the endometrium is still unclear.

AB - We measured basal body temperature, cervical mucus, follicular diameter, and serum LH, FSH, 17β-estradiol, and progesterone daily in 40 spontaneous ovulatory cycles in 27 infertile women and in 40 clomiphene citrate-induced ovulatory cycles in 31 women. The cervical score was significantly lower and the serum FSH, LH, and 17β-estradiol levels were significantly higher during the follicular phase in induced compared with spontaneous cycles. Serum progesterone was significantly higher on the 3 days preceding ovulation and the day of ovulation in the induced cycles. These increased preovulatory serum progesterone levels could contribute to the lower cervical mucus score in the induced compared with spontaneous cycle, whereas their effect on the endometrium is still unclear.

UR - http://www.scopus.com/inward/record.url?scp=0024426235&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024426235&partnerID=8YFLogxK

M3 - Article

C2 - 2503535

AN - SCOPUS:0024426235

VL - 69

SP - 681

EP - 683

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

SN - 0021-972X

IS - 3

ER -