Enhancement patterns of prostate cancer in dynamic MRI

Paolo Preziosi, Antonio Orlacchio, Guido Di Giambattista, Paolo Di Renzi, Luigi Bartolotti, Alfredo Fabiano, Enrico Cruciani, Patrizio Pasqualetti

Research output: Contribution to journalArticlepeer-review


Our objective was to analyze fast-field-echo dynamic subtracted (FFE/DS) MRI data in prostate cancer, in order to recognize enhancement patterns of tumoral tissue in comparison with non-tumoral peripheral prostatic tissue. Eleven consecutive patients with prostate cancer were proposed for radical prostatectomy. Before surgery, all patients underwent endorectal coil MRI examination. In addition to standard sequences, a dynamic study was performed by FFE/DS to evaluate tumoral behavior after Gd-DTPA rapid infusion. Analysis of the imaging was made by the means of the time/signal intensity curve obtained during early contrast medium enhancement, sampling both the abnormal enhancing focal area and the opposite lobe at the level of the main prostatic tissue. A focal area of increased enhancement was observed in the site of the tumor in all cases. The time/intensity curve sampled on this area and compared with the opposite lobe demonstrated a high confidence interval of the difference of the data: mean tumor maximal intensity 1331 (SD 187) vs normal 470 (SD 139) and mean tumor rise time 103 s (SD 30) vs normal 250 (SD 38; p

Original languageEnglish
Pages (from-to)925-930
Number of pages6
JournalEuropean Radiology
Issue number5
Publication statusPublished - May 1 2003


  • MR contrast medium
  • MR dynamic study
  • MR subtraction technique
  • Prostate MR
  • Prostatic neoplasms diagnosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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