Enhancing cranial nerves and cauda equina: An emerging magnetic resonance imaging pattern in metachromatic leukodystrophy and Krabbe disease

Giovanni Morana, R. Biancheri, M. Dirocco, M. Filocamo, M. G. Marazzi, A. Pessagno, A. Rossi

Research output: Contribution to journalArticle

Abstract

We report on three cases of infantile Krabbe disease and one case of infantile metachromatic leukodystrophy showing magnetic resonance (MR) imaging findings of diffuse and coexistent cranial nerve and cauda equina nerve roots enhancement. Such findings may be simultaneous, or even precede, typical white matter abnormalities and, in the appropriate clinical context, may facilitate an earlier diagnosis. There is a rational for the use of contrast agents and craniospinal MR imaging during the first imaging of children with a history of psychomotor regression and clinical evidence of peripheral nerve involvement to exclude differential diagnoses.

Original languageEnglish
Pages (from-to)291-294
Number of pages4
JournalNeuropediatrics
Volume40
Issue number6
DOIs
Publication statusPublished - 2009

Keywords

  • inborn errors of metabolism
  • MRI
  • peripheral nervous system

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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