Abstract
Polyoxometalates (POMs) and peptides can be conjugated to yield novel bio-hybrids with potential application as nanodrugs. However, the observed POM-induced folding of the peptide prevents its availability towards biological targets. An Anderson-Evans POM was functionalized with a bombesin analog peptide and engineered by adding a tailored hydrophilic and anionic spacer between the two moieties, to make the targeting sequence more accessible and enable an unprecedented cancer cell recognition capability. This journal is
Original language | English |
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Pages (from-to) | 4952-4957 |
Number of pages | 6 |
Journal | RSC Advances |
Volume | 11 |
Issue number | 9 |
DOIs | |
Publication status | Published - Jan 26 2021 |
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)