Ensuring sample quality for biomarker discovery studies - Use of ict tools to trace biosample life-cycle

Silvia Riondino, Patrizia Ferroni, Antonella Spila, Jhessica Alessandroni, Roberta D'Alessandro, Vincenzo Formica, David Della-Morte, Raffaele Palmirotta, Umberto Nanni, Mario Roselli, Fiorella Guadagni

Research output: Contribution to journalArticlepeer-review


The growing demand of personalized medicine marked the transition from an empirical medicine to a molecular one, aimed at predicting safer and more effective medical treatment for every patient, while minimizing adverse effects. This passage has emphasized the importance of biomarker discovery studies, and has led sample availability to assume a crucial role in biomedical research. Accordingly, a great interest in Biological Bank science has grown concomitantly. In biobanks, biological material and its accompanying data are collected, handled and stored in accordance with standard operating procedures (SOPs) and existing legislation. Sample quality is ensured by adherence to SOPs and sample whole life-cycle can be recorded by innovative tracking systems employing information technology (IT) tools for monitoring storage conditions and characterization of vast amount of data. All the above will ensure proper sample exchangeability among research facilities and will represent the starting point of all future personalized medicine-based clinical trials.

Original languageEnglish
Pages (from-to)291-300
Number of pages10
JournalCancer Genomics and Proteomics
Issue number6
Publication statusPublished - Nov 1 2015


  • Biobanking
  • Biomarker discovery
  • ICT tools
  • Review
  • Sample quality

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Cancer Research
  • Biochemistry


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