TY - JOUR
T1 - Enteral self-expandable metal stent for malignant luminal obstruction of the upper and lower gastrointestinal tract
T2 - A prospective multicentric study
AU - Masci, Enzo
AU - Viale, Edi
AU - Mangiavillano, Benedetto
AU - Contin, Guglielmo
AU - Lomazzi, Alfredo
AU - Buffoli, Federico
AU - Gatti, Mario
AU - Repaci, Giuseppe
AU - Teruzzi, Vittorio
AU - Fasoli, Renato
AU - Ravelli, Paolo
AU - Testoni, Pier Alberto
PY - 2008/4
Y1 - 2008/4
N2 - BACKGROUND: Self-expanding metal stents (SEMSs) are used to treat malignant stenosis of the gastrointestinal (GI) tract, as a safe, feasible, and minimally invasive option for reestablishing luminal patency. However, the literature offers scant prospective data on the clinical outcome of these patients. AIM: To assess the technical success, complications, and clinical outcomes of patients with a SEMS placed for malignant upper and lower GI obstruction. PATIENTS AND METHODS: A cohort of 110 patients with clinical symptoms related to malignant stenosis of the upper and lower GI tract were prospectively enrolled and SEMSs were placed endoscopically in 9 endoscopy centers. The patients were followed up and survival, oral intake, stool canalization, and late complications were recorded on days 30, 90, and 180. RESULTS: Overall, 110 patients, 38 (34.5%) with upper and 72 (65.5%) with lower GI obstruction were examined. The procedure was successful in 102 (92.7%). There were 5 early complications (96 h) occurred in 6 patients (6.3%). Median survival after stenting was 90 days (q1 30; q3 120). Placing the SEMS enabled 79.4%, 90.9%, and 100% of the patients to resume an oral diet at 30, 90, and 180 days, respectively. All patients had stool canalization until death. CONCLUSIONS: Endoscopic stenting is an effective and safe procedure for malignant luminal obstruction of the GI tract, with good clinical outcomes in patients whose survival is unfortunately short.
AB - BACKGROUND: Self-expanding metal stents (SEMSs) are used to treat malignant stenosis of the gastrointestinal (GI) tract, as a safe, feasible, and minimally invasive option for reestablishing luminal patency. However, the literature offers scant prospective data on the clinical outcome of these patients. AIM: To assess the technical success, complications, and clinical outcomes of patients with a SEMS placed for malignant upper and lower GI obstruction. PATIENTS AND METHODS: A cohort of 110 patients with clinical symptoms related to malignant stenosis of the upper and lower GI tract were prospectively enrolled and SEMSs were placed endoscopically in 9 endoscopy centers. The patients were followed up and survival, oral intake, stool canalization, and late complications were recorded on days 30, 90, and 180. RESULTS: Overall, 110 patients, 38 (34.5%) with upper and 72 (65.5%) with lower GI obstruction were examined. The procedure was successful in 102 (92.7%). There were 5 early complications (96 h) occurred in 6 patients (6.3%). Median survival after stenting was 90 days (q1 30; q3 120). Placing the SEMS enabled 79.4%, 90.9%, and 100% of the patients to resume an oral diet at 30, 90, and 180 days, respectively. All patients had stool canalization until death. CONCLUSIONS: Endoscopic stenting is an effective and safe procedure for malignant luminal obstruction of the GI tract, with good clinical outcomes in patients whose survival is unfortunately short.
KW - Lower GI tract
KW - Malignant stricture
KW - Metal stent
KW - Outcome
KW - Upper GI tract
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U2 - 10.1097/MCG.0b013e318033d30a
DO - 10.1097/MCG.0b013e318033d30a
M3 - Article
C2 - 18277900
AN - SCOPUS:41349092368
VL - 42
SP - 389
EP - 394
JO - Journal of Clinical Gastroenterology
JF - Journal of Clinical Gastroenterology
SN - 0192-0790
IS - 4
ER -