Enteral self-expandable metal stent for malignant luminal obstruction of the upper and lower gastrointestinal tract: A prospective multicentric study

Enzo Masci, Edi Viale, Benedetto Mangiavillano, Guglielmo Contin, Alfredo Lomazzi, Federico Buffoli, Mario Gatti, Giuseppe Repaci, Vittorio Teruzzi, Renato Fasoli, Paolo Ravelli, Pier Alberto Testoni

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Self-expanding metal stents (SEMSs) are used to treat malignant stenosis of the gastrointestinal (GI) tract, as a safe, feasible, and minimally invasive option for reestablishing luminal patency. However, the literature offers scant prospective data on the clinical outcome of these patients. AIM: To assess the technical success, complications, and clinical outcomes of patients with a SEMS placed for malignant upper and lower GI obstruction. PATIENTS AND METHODS: A cohort of 110 patients with clinical symptoms related to malignant stenosis of the upper and lower GI tract were prospectively enrolled and SEMSs were placed endoscopically in 9 endoscopy centers. The patients were followed up and survival, oral intake, stool canalization, and late complications were recorded on days 30, 90, and 180. RESULTS: Overall, 110 patients, 38 (34.5%) with upper and 72 (65.5%) with lower GI obstruction were examined. The procedure was successful in 102 (92.7%). There were 5 early complications (96 h) occurred in 6 patients (6.3%). Median survival after stenting was 90 days (q1 30; q3 120). Placing the SEMS enabled 79.4%, 90.9%, and 100% of the patients to resume an oral diet at 30, 90, and 180 days, respectively. All patients had stool canalization until death. CONCLUSIONS: Endoscopic stenting is an effective and safe procedure for malignant luminal obstruction of the GI tract, with good clinical outcomes in patients whose survival is unfortunately short.

Original languageEnglish
Pages (from-to)389-394
Number of pages6
JournalJournal of Clinical Gastroenterology
Volume42
Issue number4
DOIs
Publication statusPublished - Apr 2008

Keywords

  • Lower GI tract
  • Malignant stricture
  • Metal stent
  • Outcome
  • Upper GI tract

ASJC Scopus subject areas

  • Gastroenterology

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