Enucleation of pancreatic neoplasms

S. Crippa, C. Bassi, R. Salvia, M. Falconi, G. Butturini, P. Pederzoli

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

Background: Standard resections for benign and borderline neoplasms of the pancreas are associated with a significant risk of long-term functional impairment, whereas enucleation preserves healthy parenchyma and pancreatic function. The aim of this study was to evaluate postoperative and long-term oncological and functional results after pancreatic enucleation. Methods: Data collected prospectively from 61 consecutive patients who underwent pancreatic enucleation were analysed. Results: There were no deaths. A clinically significant pancreatic fistula was reported in 14 patients (23 per cent), and five patients (8 per cent) had a further operation for fistula-related complications. The most common indication for surgery was endocrine neoplasm (38 patients; 62 per cent) and two patients (3 per cent) had a final histopathological diagnosis of malignant neoplasm. At a median follow-up of 61 months no patient had developed tumour recurrence or exocrine insufficiency. Two elderly patients developed non-insulin-dependent diabetes. Conclusion: Enucleation is an effective procedure for the radical treatment of benign and borderline neoplasms of the pancreas, with good long-term outcomes.

Original languageEnglish
Pages (from-to)1254-1259
Number of pages6
JournalBritish Journal of Surgery
Volume94
Issue number10
DOIs
Publication statusPublished - Oct 2007

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Pancreatic Neoplasms
Neoplasms
Pancreas
Pancreatic Fistula
Fistula
Recurrence

ASJC Scopus subject areas

  • Surgery

Cite this

Crippa, S., Bassi, C., Salvia, R., Falconi, M., Butturini, G., & Pederzoli, P. (2007). Enucleation of pancreatic neoplasms. British Journal of Surgery, 94(10), 1254-1259. https://doi.org/10.1002/bjs.5833

Enucleation of pancreatic neoplasms. / Crippa, S.; Bassi, C.; Salvia, R.; Falconi, M.; Butturini, G.; Pederzoli, P.

In: British Journal of Surgery, Vol. 94, No. 10, 10.2007, p. 1254-1259.

Research output: Contribution to journalArticle

Crippa, S, Bassi, C, Salvia, R, Falconi, M, Butturini, G & Pederzoli, P 2007, 'Enucleation of pancreatic neoplasms', British Journal of Surgery, vol. 94, no. 10, pp. 1254-1259. https://doi.org/10.1002/bjs.5833
Crippa S, Bassi C, Salvia R, Falconi M, Butturini G, Pederzoli P. Enucleation of pancreatic neoplasms. British Journal of Surgery. 2007 Oct;94(10):1254-1259. https://doi.org/10.1002/bjs.5833
Crippa, S. ; Bassi, C. ; Salvia, R. ; Falconi, M. ; Butturini, G. ; Pederzoli, P. / Enucleation of pancreatic neoplasms. In: British Journal of Surgery. 2007 ; Vol. 94, No. 10. pp. 1254-1259.
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