Environmental modifiable risk factors for multiple sclerosis

Report from the 2016 ECTRIMS focused workshop

For the 2016 ECTRIMS Focused Workshop Group

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Multiple sclerosis (MS) is an inflammatory and neurodegenerative demyelinating disease of the central nervous system (CNS), most likely autoimmune in origin, usually beginning in early adulthood. The aetiology of the disease is not well understood; it is viewed currently as a multifactorial disease which results from complex interactions between genetic predisposition and environmental factors, of which a few are potentially modifiable. Improving our understanding of these factors can lead to new and more effective approaches to patient counselling and, possibly, prevention and management of the disease. The 2016 focused workshop of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) addressed the topic of environmental, modifiable risk factors for MS, gathering experts from around the world, to collate experimental and clinical research into environmental factors that have been associated with the disease onset and, in a few cases, disease activity and progression. A number of factors, including infections, vitamin D deficiency, diet and lifestyle factors, stress and comorbidities, were discussed. The meeting provided a forum to analyse available evidence, to identify inconsistencies and gaps in current knowledge and to suggest avenues for future research.

Original languageEnglish
JournalMultiple Sclerosis Journal
DOIs
Publication statusAccepted/In press - Jan 1 2017

Fingerprint

Multiple Sclerosis
Education
Research
Vitamin D Deficiency
Demyelinating Diseases
Genetic Predisposition to Disease
Disease Management
Neurodegenerative Diseases
Disease Progression
Life Style
Comorbidity
Counseling
Therapeutics
Central Nervous System
Diet
Infection

Keywords

  • comorbidities
  • environmental risk factors
  • infections
  • lifestyle
  • Multiple sclerosis
  • vitamin D

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Environmental modifiable risk factors for multiple sclerosis : Report from the 2016 ECTRIMS focused workshop. / For the 2016 ECTRIMS Focused Workshop Group.

In: Multiple Sclerosis Journal, 01.01.2017.

Research output: Contribution to journalArticle

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abstract = "Multiple sclerosis (MS) is an inflammatory and neurodegenerative demyelinating disease of the central nervous system (CNS), most likely autoimmune in origin, usually beginning in early adulthood. The aetiology of the disease is not well understood; it is viewed currently as a multifactorial disease which results from complex interactions between genetic predisposition and environmental factors, of which a few are potentially modifiable. Improving our understanding of these factors can lead to new and more effective approaches to patient counselling and, possibly, prevention and management of the disease. The 2016 focused workshop of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) addressed the topic of environmental, modifiable risk factors for MS, gathering experts from around the world, to collate experimental and clinical research into environmental factors that have been associated with the disease onset and, in a few cases, disease activity and progression. A number of factors, including infections, vitamin D deficiency, diet and lifestyle factors, stress and comorbidities, were discussed. The meeting provided a forum to analyse available evidence, to identify inconsistencies and gaps in current knowledge and to suggest avenues for future research.",
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