Environmental risk factors in psoriasis: The point of view of the nutritionist

Luigi Barrea, Francesca Nappi, Carolina Di Somma, Maria Cristina Savanelli, Andrea Falco, Anna Balato, Nicola Balato, Silvia Savastano

Research output: Contribution to journalReview articlepeer-review


Psoriasis is a common, chronic, immune-mediated skin disease with systemic pro-inflammatory activation, where both environmental and genetic factors contribute to its pathogenesis. Among the risk factors for psoriasis, evidence is accumulating that nutrition plays a major role, per se, in psoriasis pathogenesis. In particular, body weight, nutrition, and diet may exacerbate the clinical manifestations, or even trigger the disease. Understanding the epidemiological relationship between obesity and psoriasis is also important for delineating the risk profile for the obesity-related comorbidities commonly found among psoriatic patients. Moreover, obesity can affect both drug’s pharmacokinetics and pharmacodynamics. Additionally, the overall beneficial effects on the obesity-associated comorbidities, clinical recommendations to reduce weight and to adopt a healthy lifestyle could improve the psoriasis severity, particularly in those patients with moderate to severe disease, thus exerting additional therapeutic effects in the conventional treatment in obese patients with psoriasis. Education regarding modifiable environmental factors is essential in the treatment of this disease and represents one of the primary interventions that can affect the prognosis of patients with psoriasis. The goal is to make psoriatic patients and health care providers aware of beneficial dietary interventions. The aim of this review is to assess the relevance of the environmental factors as modifiable risk factors in psoriasis pathogenesis, with particular regard to the involvement of obesity and nutrition in the management of psoriasis, providing also specific nutrition recommendations.

Original languageEnglish
Article number743
JournalInternational Journal of Environmental Research and Public Health
Issue number7
Publication statusPublished - Jul 22 2016


  • Bioelectrical impedance analysis
  • Body composition
  • Environmental risk factors
  • Lifestyle
  • Mediterranean diet
  • Nutrition
  • Nutritionist
  • Obesity
  • Phase angle

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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