Epidermal Growth Factor (EGF) stimulates the proliferation of epithelium both in organ culture and in vivo: the topical application of the factor to the burns of mice resulted in a marked hyperplasia. The epithelium rapidly regressed to its normal thickness: this phenomenon is accomplished by a histologic increase of ATP-ase, leucinoaminopeptidase, succinodehydrogenase in the epidermal cells. In this paper we reported that EGF accelerated the repair of burns in adult mice.
|Translated title of the contribution||Enzymatic modifications of burned skin in mice after topical treatment with EGF|
|Number of pages||7|
|Publication status||Published - 1977|
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