Enzyme activities and ultrastructure of intestinal epithelium in the mouse treated with chloramphenicol.

C. Cellesi, G. M. Rossolini, P. Lusini, R. Gerli, C. Alessandrini

Research output: Contribution to journalArticle

Abstract

Several enzyme activities in the enteric mucous membrane (maltase, lactase, leucineaminopeptidase) were assayed and intestinal epithelium ultrastructure was evaluated in mice treated with chloramphenicol, per os, in different doses (50 mg/Kg and 100 mg/Kg), for 10 days. Of the enzyme activities assayed, only leucineaminopeptidase was found to be significantly lower in treated animals than in controls. Enterocyte ultrastructure and mitochondrial morphometrical parameters were not found to be significantly modified in treated animals.

Original languageEnglish
Pages (from-to)552-556
Number of pages5
JournalBollettino dell'Istituto Sieroterapico Milanese
Volume65
Issue number6
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Immunology

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