Abstract
Although it has been shown that muscle magnetic resonance imaging (MRI) improves the phenotypic characterization of patients with neuromuscular disorders and allows accurate quantification of muscle and adipose tissue distribution, to date quantitative MRI has not been used to assess the therapeutic response in clinical trials of neuromuscular diseases. We discuss quantitative MRI findings after a 6-month course of enzyme replacement therapy administered to nine patients with adult-onset glycogenosis II.
Original language | English |
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Pages (from-to) | 122-125 |
Number of pages | 4 |
Journal | Muscle and Nerve |
Volume | 40 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jul 2009 |
Keywords
- Acid maltase deficiency
- Enzyme-replacement therapy
- ERT
- Glycogenosis II
- Muscle MRI
- Pompe disease
ASJC Scopus subject areas
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)
- Physiology