EORTC/MSGERC Definitions of Invasive Fungal Diseases: Summary of Activities of the Intensive Care Unit Working Group

Matteo Bassetti, Elie Azoulay, Bart Jan Kullberg, Markus Ruhnke, Shmuel Shoham, Jose Vazquez, Daniele Roberto Giacobbe, Thierry Calandra

Research output: Contribution to journalArticlepeer-review

Abstract

The EORTC/MSGERC recently revised and updated the consensus definitions of invasive fungal disease (IFD). These definitions primarily focus on patients with cancer and stem cell or solid-organ transplant patients. They may therefore not be suitable for intensive care unit (ICU) patients. More in detail, while the definition of proven IFD applies to a broad range of hosts, the categories of probable and possible IFD were primarily designed for classical immunocompromised hosts and may therefore not be ideal for other populations. Moreover, the scope of the possible category of IFD has been diminished in the recently revised definitions for classically immunocompromised hosts. Diagnosis of IFD in the ICU presents many challenges, which are different for invasive candidiasis and for invasive aspergillosis. The aim of this article is to review progresses made in recent years and difficulties remaining in the development of definitions applicable in the ICU setting.

Original languageEnglish
Pages (from-to)S121-S127
JournalClinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume72
Issue number2
DOIs
Publication statusPublished - Mar 12 2021

Keywords

  • biomarker
  • definition
  • histology
  • invasive aspergillosis (IA)
  • invasive candidiasis (IC)

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'EORTC/MSGERC Definitions of Invasive Fungal Diseases: Summary of Activities of the Intensive Care Unit Working Group'. Together they form a unique fingerprint.

Cite this