Eosinophil lung related to allergic bronchopulmonary aspergillosis. Diagnostic and therapeutic considerations

G. Brunetti, I. Jedrychowska, A. Bossi, M. Fiori, P. Pisati, M. Guglielminetti

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Abstract

A case report of Allergic Bronchopulmonary Aspergillosis (ABPA) is described. The authors emphasize: 1) the suitability, in diagnostic phase, of high resolution computed tomography for the detection of central bronchiectasis and the usefulness of Eosinophil Cationic Protein (ECP) in monitoring the activity of disease. 2) The efficacy and the good tolerance of itraconazole (200 mg/day) as adjunctive therapy in association with steroids. Interestingly a transient remission of radiological abnormalities, pulmonary function tests, blood and alveolar hypereosinophilia as well as a reduction of IgE serum concentration, was obtained after a first period of therapy with itraconazole alone.

Original languageEnglish
Pages (from-to)203-206
Number of pages4
JournalJournal de Mycologie Medicale
Volume7
Issue number4
Publication statusPublished - 1997

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Keywords

  • Allergic bronchopulmonary aspergillosis (ABPA)
  • Itraconazole

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Microbiology

Cite this

Brunetti, G., Jedrychowska, I., Bossi, A., Fiori, M., Pisati, P., & Guglielminetti, M. (1997). Eosinophil lung related to allergic bronchopulmonary aspergillosis. Diagnostic and therapeutic considerations. Journal de Mycologie Medicale, 7(4), 203-206.