Epicardial coronary artery Doppler: Validation in the animal model

Giuseppe D'Ancona, Joost M. Hartman, Fabio Bartolozzi, Elza Van Deel, D. J G M Duncker, A. J J C Bogers, Michele Pilato, Arie P. Kappetein

Research output: Contribution to journalArticlepeer-review


The aim of the study was to validate a newly-designed epicardial coronary artery Doppler probe and test its detection of changes in coronary blood flow velocity. Left anterior descending (LAD) coronary blood flow and flow velocity were evaluated in four pigs with a pericoronary transit time flow (TTF) probe and a newly-designed epicardial Doppler micro-probe. Four consecutive measurements were taken for each of the following conditions: basal, partial stenosis, occlusion, and reperfusion of the LAD. Mean TTF value (mlymin) was 23.2±6.6 in basal condition, 16.2±5.7 after partial LAD stenosis, 0.1±0.3 during LAD occlusion, and 67.4±23.3 at reperfusion (P

Original languageEnglish
Pages (from-to)634-637
Number of pages4
JournalInteractive Cardiovascular and Thoracic Surgery
Issue number4
Publication statusPublished - Aug 2008


  • Coronary
  • Doppler
  • Flow measurement
  • Transit-time

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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