Epidemiologic surveillance for primary prevention of malignant mesothelioma

The Italian experience

M. Nesti, Alessandro Marinaccio, V. Gennaro, G. Gorini, D. Mirabelli, Carolina Mensi, E. Merler, F. Montanaro, Marina Musti, F. Pannelli, A. Romanelli, R. Tumino, A. Scarselli, S. Tosi, S. Massari, S. Iavicoli, C. Magnani, B. Terracini, A. Stura, G. Chiappino & 25 others A. C. Pesatori, D. Cavone, A. Lazzarotto, P. Viarengo, S. Candela, L. Mangone, A. M. Pezzarossi, C. Storchi, A. Seniori-Costantini, V. Cacciarini, E. Chellini, S. Silvestri, P. Mosciatti, C. Pascucci, S. Scondotto, C. Nicita, G. Dardanoni, M. Di Giorgi, A. Mira, F. Gioffrè, N. Ballarin, S. Roberti, P. Crosignani, P. G. Barbieri, T. Marras

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: The Italian National Mesothelioma Registry (ReNaM) was set up at the National Institute for Occupational Safety and Health (ISPESL) to estimate Italian incidence of malignant mesothelioma (MM), define modalities of asbestos exposures, assess impact and diffusion of MM, identify underestimated sources of environmental contamination. Objectives: To describe ReNaM activity, database dimension and epidemiological characteristics of the caselist. Methods: Regional Operating Centers (COR) in 16 Italian regions were set up to identify and investigate all cases of MM diagnosed in each region, applying national guidelines. COR collect cases in health care institutions. Occupational history, lifestyle and residence are obtained by direct interview using a standard questionnaire. Exposure modalities are classified by industrial hygienists, evaluating whether work, private life or any particular environmental condition could have involved asbestos exposure. Results: Data refer to 3,446 cases collected in 9 Italian regions during 1993-2001. Pleural mesothelioma affected 94% cases, pleural/peritoneal ratio was 16:1. Gender ratio (M/F) was 2.7:1 (1.3:1 for peritoneum). There was a variety of occupational exposures, some already known as high risk sectors and others unexpected. The most common exposures occurred in building and construction, metallurgy and steel, shipbuilding, and railway stock. High risk categories were encountered such as bricklayers, plumbers, carpenters, electricians, welders, installers and maintenance workers in metallurgy and the steel industry, general labourers, tool makers and painters in shipbuilding/repair/demolition. Conclusions: Despite some ReNam's limitations, identification of MM cases and analysis of modality of exposure, with standardized criteria, are a fundamental tool for primary prevention of asbestos related diseases.

Original languageEnglish
Pages (from-to)338-346
Number of pages9
JournalMedicina del Lavoro
Volume96
Issue number4
Publication statusPublished - 2005

Fingerprint

Epidemiological Monitoring
Primary Prevention
Asbestos
Metallurgy
Steel
Mesothelioma
National Institute for Occupational Safety and Health (U.S.)
Peritoneum
Occupational Exposure
Registries
Life Style
Industry
Maintenance
Databases
Guidelines
Interviews
Delivery of Health Care
Malignant Mesothelioma
Incidence

Keywords

  • Epidemiologic surveillance
  • Mesothelioma
  • National Registries

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Nesti, M., Marinaccio, A., Gennaro, V., Gorini, G., Mirabelli, D., Mensi, C., ... Marras, T. (2005). Epidemiologic surveillance for primary prevention of malignant mesothelioma: The Italian experience. Medicina del Lavoro, 96(4), 338-346.

Epidemiologic surveillance for primary prevention of malignant mesothelioma : The Italian experience. / Nesti, M.; Marinaccio, Alessandro; Gennaro, V.; Gorini, G.; Mirabelli, D.; Mensi, Carolina; Merler, E.; Montanaro, F.; Musti, Marina; Pannelli, F.; Romanelli, A.; Tumino, R.; Scarselli, A.; Tosi, S.; Massari, S.; Iavicoli, S.; Magnani, C.; Terracini, B.; Stura, A.; Chiappino, G.; Pesatori, A. C.; Cavone, D.; Lazzarotto, A.; Viarengo, P.; Candela, S.; Mangone, L.; Pezzarossi, A. M.; Storchi, C.; Seniori-Costantini, A.; Cacciarini, V.; Chellini, E.; Silvestri, S.; Mosciatti, P.; Pascucci, C.; Scondotto, S.; Nicita, C.; Dardanoni, G.; Di Giorgi, M.; Mira, A.; Gioffrè, F.; Ballarin, N.; Roberti, S.; Crosignani, P.; Barbieri, P. G.; Marras, T.

In: Medicina del Lavoro, Vol. 96, No. 4, 2005, p. 338-346.

Research output: Contribution to journalArticle

Nesti, M, Marinaccio, A, Gennaro, V, Gorini, G, Mirabelli, D, Mensi, C, Merler, E, Montanaro, F, Musti, M, Pannelli, F, Romanelli, A, Tumino, R, Scarselli, A, Tosi, S, Massari, S, Iavicoli, S, Magnani, C, Terracini, B, Stura, A, Chiappino, G, Pesatori, AC, Cavone, D, Lazzarotto, A, Viarengo, P, Candela, S, Mangone, L, Pezzarossi, AM, Storchi, C, Seniori-Costantini, A, Cacciarini, V, Chellini, E, Silvestri, S, Mosciatti, P, Pascucci, C, Scondotto, S, Nicita, C, Dardanoni, G, Di Giorgi, M, Mira, A, Gioffrè, F, Ballarin, N, Roberti, S, Crosignani, P, Barbieri, PG & Marras, T 2005, 'Epidemiologic surveillance for primary prevention of malignant mesothelioma: The Italian experience', Medicina del Lavoro, vol. 96, no. 4, pp. 338-346.
Nesti M, Marinaccio A, Gennaro V, Gorini G, Mirabelli D, Mensi C et al. Epidemiologic surveillance for primary prevention of malignant mesothelioma: The Italian experience. Medicina del Lavoro. 2005;96(4):338-346.
Nesti, M. ; Marinaccio, Alessandro ; Gennaro, V. ; Gorini, G. ; Mirabelli, D. ; Mensi, Carolina ; Merler, E. ; Montanaro, F. ; Musti, Marina ; Pannelli, F. ; Romanelli, A. ; Tumino, R. ; Scarselli, A. ; Tosi, S. ; Massari, S. ; Iavicoli, S. ; Magnani, C. ; Terracini, B. ; Stura, A. ; Chiappino, G. ; Pesatori, A. C. ; Cavone, D. ; Lazzarotto, A. ; Viarengo, P. ; Candela, S. ; Mangone, L. ; Pezzarossi, A. M. ; Storchi, C. ; Seniori-Costantini, A. ; Cacciarini, V. ; Chellini, E. ; Silvestri, S. ; Mosciatti, P. ; Pascucci, C. ; Scondotto, S. ; Nicita, C. ; Dardanoni, G. ; Di Giorgi, M. ; Mira, A. ; Gioffrè, F. ; Ballarin, N. ; Roberti, S. ; Crosignani, P. ; Barbieri, P. G. ; Marras, T. / Epidemiologic surveillance for primary prevention of malignant mesothelioma : The Italian experience. In: Medicina del Lavoro. 2005 ; Vol. 96, No. 4. pp. 338-346.
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abstract = "Background: The Italian National Mesothelioma Registry (ReNaM) was set up at the National Institute for Occupational Safety and Health (ISPESL) to estimate Italian incidence of malignant mesothelioma (MM), define modalities of asbestos exposures, assess impact and diffusion of MM, identify underestimated sources of environmental contamination. Objectives: To describe ReNaM activity, database dimension and epidemiological characteristics of the caselist. Methods: Regional Operating Centers (COR) in 16 Italian regions were set up to identify and investigate all cases of MM diagnosed in each region, applying national guidelines. COR collect cases in health care institutions. Occupational history, lifestyle and residence are obtained by direct interview using a standard questionnaire. Exposure modalities are classified by industrial hygienists, evaluating whether work, private life or any particular environmental condition could have involved asbestos exposure. Results: Data refer to 3,446 cases collected in 9 Italian regions during 1993-2001. Pleural mesothelioma affected 94{\%} cases, pleural/peritoneal ratio was 16:1. Gender ratio (M/F) was 2.7:1 (1.3:1 for peritoneum). There was a variety of occupational exposures, some already known as high risk sectors and others unexpected. The most common exposures occurred in building and construction, metallurgy and steel, shipbuilding, and railway stock. High risk categories were encountered such as bricklayers, plumbers, carpenters, electricians, welders, installers and maintenance workers in metallurgy and the steel industry, general labourers, tool makers and painters in shipbuilding/repair/demolition. Conclusions: Despite some ReNam's limitations, identification of MM cases and analysis of modality of exposure, with standardized criteria, are a fundamental tool for primary prevention of asbestos related diseases.",
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author = "M. Nesti and Alessandro Marinaccio and V. Gennaro and G. Gorini and D. Mirabelli and Carolina Mensi and E. Merler and F. Montanaro and Marina Musti and F. Pannelli and A. Romanelli and R. Tumino and A. Scarselli and S. Tosi and S. Massari and S. Iavicoli and C. Magnani and B. Terracini and A. Stura and G. Chiappino and Pesatori, {A. C.} and D. Cavone and A. Lazzarotto and P. Viarengo and S. Candela and L. Mangone and Pezzarossi, {A. M.} and C. Storchi and A. Seniori-Costantini and V. Cacciarini and E. Chellini and S. Silvestri and P. Mosciatti and C. Pascucci and S. Scondotto and C. Nicita and G. Dardanoni and {Di Giorgi}, M. and A. Mira and F. Gioffr{\`e} and N. Ballarin and S. Roberti and P. Crosignani and Barbieri, {P. G.} and T. Marras",
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T1 - Epidemiologic surveillance for primary prevention of malignant mesothelioma

T2 - The Italian experience

AU - Nesti, M.

AU - Marinaccio, Alessandro

AU - Gennaro, V.

AU - Gorini, G.

AU - Mirabelli, D.

AU - Mensi, Carolina

AU - Merler, E.

AU - Montanaro, F.

AU - Musti, Marina

AU - Pannelli, F.

AU - Romanelli, A.

AU - Tumino, R.

AU - Scarselli, A.

AU - Tosi, S.

AU - Massari, S.

AU - Iavicoli, S.

AU - Magnani, C.

AU - Terracini, B.

AU - Stura, A.

AU - Chiappino, G.

AU - Pesatori, A. C.

AU - Cavone, D.

AU - Lazzarotto, A.

AU - Viarengo, P.

AU - Candela, S.

AU - Mangone, L.

AU - Pezzarossi, A. M.

AU - Storchi, C.

AU - Seniori-Costantini, A.

AU - Cacciarini, V.

AU - Chellini, E.

AU - Silvestri, S.

AU - Mosciatti, P.

AU - Pascucci, C.

AU - Scondotto, S.

AU - Nicita, C.

AU - Dardanoni, G.

AU - Di Giorgi, M.

AU - Mira, A.

AU - Gioffrè, F.

AU - Ballarin, N.

AU - Roberti, S.

AU - Crosignani, P.

AU - Barbieri, P. G.

AU - Marras, T.

PY - 2005

Y1 - 2005

N2 - Background: The Italian National Mesothelioma Registry (ReNaM) was set up at the National Institute for Occupational Safety and Health (ISPESL) to estimate Italian incidence of malignant mesothelioma (MM), define modalities of asbestos exposures, assess impact and diffusion of MM, identify underestimated sources of environmental contamination. Objectives: To describe ReNaM activity, database dimension and epidemiological characteristics of the caselist. Methods: Regional Operating Centers (COR) in 16 Italian regions were set up to identify and investigate all cases of MM diagnosed in each region, applying national guidelines. COR collect cases in health care institutions. Occupational history, lifestyle and residence are obtained by direct interview using a standard questionnaire. Exposure modalities are classified by industrial hygienists, evaluating whether work, private life or any particular environmental condition could have involved asbestos exposure. Results: Data refer to 3,446 cases collected in 9 Italian regions during 1993-2001. Pleural mesothelioma affected 94% cases, pleural/peritoneal ratio was 16:1. Gender ratio (M/F) was 2.7:1 (1.3:1 for peritoneum). There was a variety of occupational exposures, some already known as high risk sectors and others unexpected. The most common exposures occurred in building and construction, metallurgy and steel, shipbuilding, and railway stock. High risk categories were encountered such as bricklayers, plumbers, carpenters, electricians, welders, installers and maintenance workers in metallurgy and the steel industry, general labourers, tool makers and painters in shipbuilding/repair/demolition. Conclusions: Despite some ReNam's limitations, identification of MM cases and analysis of modality of exposure, with standardized criteria, are a fundamental tool for primary prevention of asbestos related diseases.

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KW - Epidemiologic surveillance

KW - Mesothelioma

KW - National Registries

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