Epidemiological aspects of inflammatory bowel disease in a north Italian population: A 4-year prospective study

Tullio Ranzi, Paolo Bodini, Alessandro Zambelli, Patrizia Politi, Guido Lupinacci, Maria Cristina Campanini, Anna Lisa Dal Lago, Dario Lisciandrano, Paolo A. Bianchi

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Objective: To determine the incidence and clinical characteristics at presentation of inflammatory bower disease (IBD) in a defined area of north Italy. Design: A 4-year prospective population-based epidemiological study. Setting: An area in Lombardia defined by the National Health Service scheme with about 294 000 inhabitants, two referral hospitals and 259 general practitioners (GPs). Patients: Subjects presenting to a GP with symptoms compatible with IBD underwent a diagnostic work-up at one of the referral hospitals. Those with ulcerative colitis (UC), Crohn's disease (CD) or indeterminate colitis diagnosed according to a defined protocol were included, as were residents of the area with IBD diagnosed elsewhere. Rigid case ascertainment methods were used. Patients were followed for one year; 125 patients were identified. Results: The patient ascertainment rate was constant over the 4 years; UC was diagnosed in 82 patients, CD in 40, and indeterminate colitis in three. The mean annual incidence of IBD for the whole period was 10.6/105 inhabitants (95% confidence limits, 7.2-15.1), 7.0/105 for UC (4.3-10.7) and 3.4/105 (1.6-6.3) for CD. The mean interval between onset of symptoms and diagnosis was under 6 months. The clinical characteristics of our patients were similar to those of north European and American series. Conclusion: The incidence of IBD was higher than previously observed in Italy but was still lower than in some north European countries and in the USA. Our data could be used as a basis for future longitudinal studies and in international comparative investigations.

Original languageEnglish
Pages (from-to)657-661
Number of pages5
JournalEuropean Journal of Gastroenterology and Hepatology
Volume8
Issue number7
Publication statusPublished - 1996

Fingerprint

Inflammatory Bowel Diseases
Prospective Studies
Ulcerative Colitis
Crohn Disease
Population
Colitis
General Practitioners
Italy
Incidence
Referral and Consultation
National Health Programs
Longitudinal Studies
Epidemiologic Studies

Keywords

  • Crohn's disease
  • Epidemiology
  • Incidence
  • Inflammatory bowel disease
  • Ulcerative colitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Ranzi, T., Bodini, P., Zambelli, A., Politi, P., Lupinacci, G., Campanini, M. C., ... Bianchi, P. A. (1996). Epidemiological aspects of inflammatory bowel disease in a north Italian population: A 4-year prospective study. European Journal of Gastroenterology and Hepatology, 8(7), 657-661.

Epidemiological aspects of inflammatory bowel disease in a north Italian population : A 4-year prospective study. / Ranzi, Tullio; Bodini, Paolo; Zambelli, Alessandro; Politi, Patrizia; Lupinacci, Guido; Campanini, Maria Cristina; Dal Lago, Anna Lisa; Lisciandrano, Dario; Bianchi, Paolo A.

In: European Journal of Gastroenterology and Hepatology, Vol. 8, No. 7, 1996, p. 657-661.

Research output: Contribution to journalArticle

Ranzi, T, Bodini, P, Zambelli, A, Politi, P, Lupinacci, G, Campanini, MC, Dal Lago, AL, Lisciandrano, D & Bianchi, PA 1996, 'Epidemiological aspects of inflammatory bowel disease in a north Italian population: A 4-year prospective study', European Journal of Gastroenterology and Hepatology, vol. 8, no. 7, pp. 657-661.
Ranzi, Tullio ; Bodini, Paolo ; Zambelli, Alessandro ; Politi, Patrizia ; Lupinacci, Guido ; Campanini, Maria Cristina ; Dal Lago, Anna Lisa ; Lisciandrano, Dario ; Bianchi, Paolo A. / Epidemiological aspects of inflammatory bowel disease in a north Italian population : A 4-year prospective study. In: European Journal of Gastroenterology and Hepatology. 1996 ; Vol. 8, No. 7. pp. 657-661.
@article{662c4ba6e606432eb2920e4d77da2824,
title = "Epidemiological aspects of inflammatory bowel disease in a north Italian population: A 4-year prospective study",
abstract = "Objective: To determine the incidence and clinical characteristics at presentation of inflammatory bower disease (IBD) in a defined area of north Italy. Design: A 4-year prospective population-based epidemiological study. Setting: An area in Lombardia defined by the National Health Service scheme with about 294 000 inhabitants, two referral hospitals and 259 general practitioners (GPs). Patients: Subjects presenting to a GP with symptoms compatible with IBD underwent a diagnostic work-up at one of the referral hospitals. Those with ulcerative colitis (UC), Crohn's disease (CD) or indeterminate colitis diagnosed according to a defined protocol were included, as were residents of the area with IBD diagnosed elsewhere. Rigid case ascertainment methods were used. Patients were followed for one year; 125 patients were identified. Results: The patient ascertainment rate was constant over the 4 years; UC was diagnosed in 82 patients, CD in 40, and indeterminate colitis in three. The mean annual incidence of IBD for the whole period was 10.6/105 inhabitants (95{\%} confidence limits, 7.2-15.1), 7.0/105 for UC (4.3-10.7) and 3.4/105 (1.6-6.3) for CD. The mean interval between onset of symptoms and diagnosis was under 6 months. The clinical characteristics of our patients were similar to those of north European and American series. Conclusion: The incidence of IBD was higher than previously observed in Italy but was still lower than in some north European countries and in the USA. Our data could be used as a basis for future longitudinal studies and in international comparative investigations.",
keywords = "Crohn's disease, Epidemiology, Incidence, Inflammatory bowel disease, Ulcerative colitis",
author = "Tullio Ranzi and Paolo Bodini and Alessandro Zambelli and Patrizia Politi and Guido Lupinacci and Campanini, {Maria Cristina} and {Dal Lago}, {Anna Lisa} and Dario Lisciandrano and Bianchi, {Paolo A.}",
year = "1996",
language = "English",
volume = "8",
pages = "657--661",
journal = "European Journal of Gastroenterology and Hepatology",
issn = "0954-691X",
publisher = "Lippincott Williams and Wilkins",
number = "7",

}

TY - JOUR

T1 - Epidemiological aspects of inflammatory bowel disease in a north Italian population

T2 - A 4-year prospective study

AU - Ranzi, Tullio

AU - Bodini, Paolo

AU - Zambelli, Alessandro

AU - Politi, Patrizia

AU - Lupinacci, Guido

AU - Campanini, Maria Cristina

AU - Dal Lago, Anna Lisa

AU - Lisciandrano, Dario

AU - Bianchi, Paolo A.

PY - 1996

Y1 - 1996

N2 - Objective: To determine the incidence and clinical characteristics at presentation of inflammatory bower disease (IBD) in a defined area of north Italy. Design: A 4-year prospective population-based epidemiological study. Setting: An area in Lombardia defined by the National Health Service scheme with about 294 000 inhabitants, two referral hospitals and 259 general practitioners (GPs). Patients: Subjects presenting to a GP with symptoms compatible with IBD underwent a diagnostic work-up at one of the referral hospitals. Those with ulcerative colitis (UC), Crohn's disease (CD) or indeterminate colitis diagnosed according to a defined protocol were included, as were residents of the area with IBD diagnosed elsewhere. Rigid case ascertainment methods were used. Patients were followed for one year; 125 patients were identified. Results: The patient ascertainment rate was constant over the 4 years; UC was diagnosed in 82 patients, CD in 40, and indeterminate colitis in three. The mean annual incidence of IBD for the whole period was 10.6/105 inhabitants (95% confidence limits, 7.2-15.1), 7.0/105 for UC (4.3-10.7) and 3.4/105 (1.6-6.3) for CD. The mean interval between onset of symptoms and diagnosis was under 6 months. The clinical characteristics of our patients were similar to those of north European and American series. Conclusion: The incidence of IBD was higher than previously observed in Italy but was still lower than in some north European countries and in the USA. Our data could be used as a basis for future longitudinal studies and in international comparative investigations.

AB - Objective: To determine the incidence and clinical characteristics at presentation of inflammatory bower disease (IBD) in a defined area of north Italy. Design: A 4-year prospective population-based epidemiological study. Setting: An area in Lombardia defined by the National Health Service scheme with about 294 000 inhabitants, two referral hospitals and 259 general practitioners (GPs). Patients: Subjects presenting to a GP with symptoms compatible with IBD underwent a diagnostic work-up at one of the referral hospitals. Those with ulcerative colitis (UC), Crohn's disease (CD) or indeterminate colitis diagnosed according to a defined protocol were included, as were residents of the area with IBD diagnosed elsewhere. Rigid case ascertainment methods were used. Patients were followed for one year; 125 patients were identified. Results: The patient ascertainment rate was constant over the 4 years; UC was diagnosed in 82 patients, CD in 40, and indeterminate colitis in three. The mean annual incidence of IBD for the whole period was 10.6/105 inhabitants (95% confidence limits, 7.2-15.1), 7.0/105 for UC (4.3-10.7) and 3.4/105 (1.6-6.3) for CD. The mean interval between onset of symptoms and diagnosis was under 6 months. The clinical characteristics of our patients were similar to those of north European and American series. Conclusion: The incidence of IBD was higher than previously observed in Italy but was still lower than in some north European countries and in the USA. Our data could be used as a basis for future longitudinal studies and in international comparative investigations.

KW - Crohn's disease

KW - Epidemiology

KW - Incidence

KW - Inflammatory bowel disease

KW - Ulcerative colitis

UR - http://www.scopus.com/inward/record.url?scp=0029899370&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029899370&partnerID=8YFLogxK

M3 - Article

C2 - 8853254

AN - SCOPUS:0029899370

VL - 8

SP - 657

EP - 661

JO - European Journal of Gastroenterology and Hepatology

JF - European Journal of Gastroenterology and Hepatology

SN - 0954-691X

IS - 7

ER -