Epidemiological correlates of preterm premature rupture of membranes

A. Spinillo, S. Nicola, G. Piazzi, K. Ghazal, L. Colonna, F. Baltaro

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To study the clinical risk factors for preterm premature rupture of membranes (PROM). Method: We conducted a case-control study of 138 patients with PROM between 24 and 35 weeks' gestation and 267 control subjects. Results: In stepwise multiple logistic regression models, the population of cases was more likely to be of low social class. Other risk factors for PROM were smoking in pregnancy, 1st or 2nd-3rd trimester hemorrhages, cervical incompetence and a documented cervico-vaginal infection during index pregnancy. First trimester hemorrhage and a documented cervico-vaginal infection during index pregnancy were associated with preterm PROM both in nulliparous and in multiparous women. Conclusion: Few potentially remediable risk factors are associated with the occurrence of preterm PROM.

Original languageEnglish
Pages (from-to)7-15
Number of pages9
JournalInternational Journal of Gynecology and Obstetrics
Volume47
Issue number1
DOIs
Publication statusPublished - 1994

Keywords

  • 1st trimester hemorrhage
  • Premature rupture of membranes
  • Risk factors
  • Vaginal infection

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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