Inchiesta epidemiologica sulle interstiziopatie polmonari in Italia: Dati e risultati a macchia di leopardo

Translated title of the contribution: Epidemiological survey on interstitial lung disease in Italy: Leopard-spot-like data and results

G. Rizzato, F. Bariffi, M. Luisetti, R. Trisolini, M. Boccieri, F. Mazza, R. Ukmar, M. Nabergoi, C. Agostini, G. Semenzato, G. Bertorelli, D. Olivieri, P. Rossi, F. De Benedetto, R. Liberati, R. Cioffi, E. Catena, G. D'Amato, A. Petraglia, M. ScarpittaC. Tranfa, G. Vero, G. Girbino, F. Ginesu, L. Rosetti, M. Ledda

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: Retrospective survey on the epidemiology of interstitial lung diseases in Italy, and how the diagnosis is reached. Methods and patients: A questionnaire has been sent to 34 Centres. Seventeen replies have described 4867 patients, investigated starting from a year ranging from 1978 to 1996. Results: A diagnosis has not been reached in 20% of cases, due to late arrival of the patient (too severe, 299 cases), non-diagnostic biopsy (228), refusal of biopsy (103), reason not described (68). The most used is transbronchial biopsy, but its diagnostic yield is 50% only, with surprising variability in the different Centres (0 to 90%). Videothoracoscopy is active in 8 Centres only. The most frequent diseases are sarcoidosis (2199 cases), idiopathic fibrosis (805) and pneumoconiosis (417). Patients in follow-up are 27.9%. Conclusion: The diagnostic work up has a number of points of concern due to: a) the delay with which many patients are sent to the pneumologist; b) the low diagnostic yield of transbronchial biopsy; c) the possible low interest or experience of a number of pathologists; d) the reluctance, after a negative transbronchial biopsy, to carry out mediastinoscopy when the suspect is sarcoidosis (stage I and II), and VATS when the suspect is idiopathic fibrosis.

Translated title of the contributionEpidemiological survey on interstitial lung disease in Italy: Leopard-spot-like data and results
Original languageItalian
Pages (from-to)20-24
Number of pages5
JournalInternista
Volume7
Issue number1
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Internal Medicine

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