Epidemiology and risk factors

Chiara Bondi, Fabio Barra, Simone Ferrero

Research output: Chapter in Book/Report/Conference proceedingChapter


Endometrial cancer (EC) is a very common neoplasia among women, being the fourth cause of cancer in the USA and the sixth in the world. EC is classified into type I disease, which is estrogen related and generally has a better prognosis; and type II disease, which is more independent of hormonal effects and has a poor prognosis with a more aggressive course. The risk factors of EC are several: constitutional factors (first of all obesity), diseases (such as diabetes mellitus, metabolic syndrome, and polycystic ovary syndrome), environmental factors (fatrich diet and cadmium exposure) and specific genetic diseases (Linch syndrome, Cowden syndrome, and HBOC syndrome). The importance of correct lifestyle in reducing the incidence of this cancer has been demonstrated.

Original languageEnglish
Title of host publicationEndometrial Cancer
Subtitle of host publicationRisk Factors, Management and Prognosis
PublisherNova Science Publishers, Inc.
Number of pages24
ISBN (Electronic)9781536138887
ISBN (Print)9781536138870
Publication statusPublished - Jan 1 2018


  • Endometrial cancer
  • Genetic syndrome
  • Protective factors
  • Risk factors
  • Type I endometrial cancer
  • Type II endometrial cancer

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Bondi, C., Barra, F., & Ferrero, S. (2018). Epidemiology and risk factors. In Endometrial Cancer: Risk Factors, Management and Prognosis (pp. 1-24). Nova Science Publishers, Inc..