TY - JOUR
T1 - Epidemiology and risk factors of pancreatic cancer
AU - Capasso, Mario
AU - Franceschi, Marilisa
AU - Rodriguez-Castro, Kryssia Isabel
AU - Crafa, Pellegrino
AU - Cambiè, Ginevra
AU - Miraglia, Chiara
AU - Barchi, Alberto
AU - Nouvenne, Antonio
AU - Leandro, Gioacchino
AU - Meschi, Tiziana
AU - De’ Angelis, Gian Luigi
AU - Di Mario, Francesco
PY - 2018/1/1
Y1 - 2018/1/1
N2 - The most frequent pancreatic cancer is pancreatic adenocarcinoma. It has high and early locally and distant invasiveness; this is the reason why it often shows little sign or symptoms in early stage and poor prognosis after the diagnosis, frequently in advanced stage. Although it is possible to detect this tumor in early stage because of its neoplastic precursor (PanINs). Epidemiological data shows that pancreatic cancer is not very common but obvious it is one of the most neoplastic death-cause in the world. The trend of incidence is quite increasing through years, proportionally to the increase of risk factors. About risk factors, it is not easy to detect in all the cases but it is known the role of some of that: there are hereditary risk factors, such as genetic pattern like HBOC, HNPCC, FAP, PJS, FAMMM, HP and CF and environmental ones (modifiable) such as smoke, alcohol consumption, chronic pancreatitis, obesity and diabetes mellitus. This narrative review aims to analyze the epidemiological data of pancreatic cancer and associated risk factors. (www.actabiomedica.it).
AB - The most frequent pancreatic cancer is pancreatic adenocarcinoma. It has high and early locally and distant invasiveness; this is the reason why it often shows little sign or symptoms in early stage and poor prognosis after the diagnosis, frequently in advanced stage. Although it is possible to detect this tumor in early stage because of its neoplastic precursor (PanINs). Epidemiological data shows that pancreatic cancer is not very common but obvious it is one of the most neoplastic death-cause in the world. The trend of incidence is quite increasing through years, proportionally to the increase of risk factors. About risk factors, it is not easy to detect in all the cases but it is known the role of some of that: there are hereditary risk factors, such as genetic pattern like HBOC, HNPCC, FAP, PJS, FAMMM, HP and CF and environmental ones (modifiable) such as smoke, alcohol consumption, chronic pancreatitis, obesity and diabetes mellitus. This narrative review aims to analyze the epidemiological data of pancreatic cancer and associated risk factors. (www.actabiomedica.it).
KW - Epidemiology
KW - Pancreatic adenocarcinoma
KW - Pancreatic cancer
KW - Risk factors
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U2 - 10.23750/abm.v89i9-S.7923
DO - 10.23750/abm.v89i9-S.7923
M3 - Review article
C2 - 30561407
AN - SCOPUS:85058762516
VL - 89
SP - 141
EP - 146
JO - Acta Biomedica de l'Ateneo Parmense
JF - Acta Biomedica de l'Ateneo Parmense
SN - 0392-4203
ER -