Epidemiology of acute promyelocytic leukemia in Italy

G. Avvisati, A. Mele, M. A. Stazi, M. L. Vegna, P. Pasquini, F. Mandelli, B. Rotoli, G. De Rosa, G. Papa, A. Venditti, P. Citarrella, M. Tambone Reyes, E. Ascari, R. Invernizzi, A. Cajozzo, M. Musso, A. Alberti, A. Peta, P. Rossi Ferrini

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Abstract

This retrospective epidemiologic study on 256 cases of acute promyelocytic leukemia (APL) observed in 20 Italian hematology centers between 1980 and 1988 demonstrated that APL is different from the other acute non-lymphocytic leukemias (ANLL). The male/female ratio was 0.9; median age at diagnosis was 40 years (with 80% of patients between 15 and 54 years of age). The minimal annual incidence of APL in Italy per 1,000,000 inhabitants was estimated to be 0.6; an increased incidence was observed in spring and in autumn. The overall median survival duration of APL patients was 12.6 months. From an epidemiological point of view APL is a distinctive subtype of ANLL.

Original languageEnglish
Pages (from-to)405-408
Number of pages4
JournalAnnals of Oncology
Volume2
Issue number6
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Public Health, Environmental and Occupational Health
  • Neuropsychology and Physiological Psychology
  • Hematology

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