Epidemiology of melanoma: Is it still epidemic? What is the role of the sun, sunbeds, Vit D, betablocks, and others?

Vincenzo De Giorgi, Alessia Gori, Marta Grazzini, Susanna Rossari, Teresa Oranges, Anna Sara Longo, Torello Lotti, Sara Gandini

Research output: Contribution to journalArticlepeer-review

Abstract

The incidence of cutaneous malignant melanoma is continuously increasing worldwide, but only minimal changes in mortality have been observed. This phenomenon has brought into question whether this increased incidence reflects a true or apparent melanoma epidemic. The most recent data suggest that this epidemiological trend may be explained by the existence of a certain degree of melanoma overdiagnosis, especially of thin lesions, which probably would never progress to advanced disease if left untreated. However, acute sun exposure and widespread use of sunbeds may also justify the increase in melanoma incidence. Recently, both vitamin D and beta-blocker use seem to play a beneficial role in melanoma progression.

Original languageEnglish
Pages (from-to)392-396
Number of pages5
JournalDermatologic Therapy
Volume25
Issue number5
DOIs
Publication statusPublished - Sep 2012

Keywords

  • beta-blockers
  • epidemiology
  • melanoma
  • sun
  • vitamin D

ASJC Scopus subject areas

  • Dermatology

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