Epidemiology of progressive supranuclear palsy

N. Vanacore, V. Bonifati, C. Colosimo, G. Fabbrini, G. De Michele, R. Marconi, D. Nicholl, N. Locuratolo, S. Romano, G. Talarico, F. Stocchi, U. Bonuccelli, P. Lamberti, P. Vieregge, G. Meco

Research output: Contribution to journalArticlepeer-review

Abstract

Progressive supranuclear palsy (PSP) is a rare form of parkinsonism. The incidence rates are about 0.3-1.1 cases per 100 000 persons. The only two case-control studies performed up to now show conflictual results as regards education and residence in rural areas. Recently, a cluster of PSP and atypical parkinsonism has been observed in French Antilles. The hypothesis is that a consumption of both tropical fruit and herbal tea may be associated with PSP onset. Some PSP families with a probably autosomal dominant transmission have been described. A high frequency of a tau haplotype (H1/H1) associated with PSP is reported by some authors. The significance of this association is still not clear. We have performed a case-control study on 58 PSP cases, 116 hospital controls and 58 population controls.

Original languageEnglish
Pages (from-to)101-103
Number of pages3
JournalNeurological Sciences
Volume22
Issue number1
DOIs
Publication statusPublished - Feb 2001

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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