Epidemiology of sudden cardiac death in Cameroon: Rationale and design of the Douala-SUD survey

Aimé Bonny, Dominique Noah Noah, Marcus Ngantcha, Robinson Ateh, Cécile Saka, Jonas Wa, Réné Fonga, Sylvie Ndongo Amougou, Bo Gregers Winkel, Pier Lambiase, Silvia G. Priori

Research output: Contribution to journalArticle

Abstract

Background The burden of sudden unexplained death in sub-Saharan Africa is unknown. Aim The aim of this study is to establish the epidemiology of sudden cardiac death in Cameroon. Methods The Douala sudden unexplained death (Douala-SUD) study is a prospective, multiple-source, community-based surveillance of all cases of unexpected death (<24 hours from onset of symptoms) occurring in victims aged > 15 years. After approval from institutional boards, all deaths occurring in residents of four areas of Douala city will be checked for circumstances of death and past medical history. Subjects who die naturally will be further investigated. Unexpected death victims will be checked for detailed demographic, clinical, electrocardiographic, echocardiographic and biological records. Autopsy background and genetic analysis (postmortem or in first relatives if the young victim is aged <40 years) will be performed as far as possible. Finally, the use of cardiopulmonary resuscitation efforts during the timeframe of sudden cardiac arrest will also be evaluated. Conclusion The Douala-SUD study will provide comprehensive, contemporary data on the epidemiology of sudden unexplained and cardiac death in sub-Saharan Africa and will help in the development of strategies to prevent and manage cardiac arrest in Cameroon as well as in other sub-Saharan countries.

Original languageEnglish
Pages (from-to)433-442
Number of pages10
JournalArchives of Cardiovascular Diseases
Volume107
Issue number8-9
DOIs
Publication statusPublished - 2014

Keywords

  • Cardiac arrest
  • Coronary artery disease
  • Sub-Saharan Africa
  • Sudden unexplained death
  • Ventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

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    Bonny, A., Noah, D. N., Ngantcha, M., Ateh, R., Saka, C., Wa, J., Fonga, R., Amougou, S. N., Winkel, B. G., Lambiase, P., & Priori, S. G. (2014). Epidemiology of sudden cardiac death in Cameroon: Rationale and design of the Douala-SUD survey. Archives of Cardiovascular Diseases, 107(8-9), 433-442. https://doi.org/10.1016/j.acvd.2014.05.005