EPIDERMOLISI BOLLOSA ACQUISITA. UN CASO DI ASSOCIAZIONE CON COLITE ULCEROSA ED ARTRITE ENTEROPATICA

Translated title of the contribution: Epidermolysis bullosa acquisita: A case associated with ulcerative colitis and enteropathic arthritis

A. Rossi, E. Berti, R. Vendrami

Research output: Contribution to journalArticle

Abstract

A patient with epidermolysis bullosa acquisita (EBA) is reported. A 34 year old male patient had been showing for seven years recurrent bullae in areas exposed to mild trauma that left atrophic scars and milia. Direct immunofluorescence demonstrated the presence of granular deposits of IgG, IgA and C3 at the dermal-epidermal junction. In the electron microscope a thick layer of amorphous material was demonstrated at the dermal side of the basal lamina. When first observed in our department (Oct. 1978) EBA was associated with ulcerative colitis and enteropathic arthritis. The data confirm that EBA is a clinical entity unrelated to the group of pemphygoid diseases. The reported association with systemic diseases involving immunological disorders is discussed. The possibility that the three concurrent diseases observed in this patient are based on single pathogenetic mechanism is examined.

Translated title of the contributionEpidermolysis bullosa acquisita: A case associated with ulcerative colitis and enteropathic arthritis
Original languageItalian
Pages (from-to)463-470
Number of pages8
JournalGiornale Italiano di Dermatologia e Venereologia
Volume115
Issue number9
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Dermatology

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