Epilepsia partialis continua in a case of MELAS: Clinical and neurophysiological study

P. Veggiotti, V. Colamaria, B. Dalla Bernardina, A. Martelli, D. Mangione, G. Lanzi

Research output: Contribution to journalArticlepeer-review


There are few reports in the literature dealing with the association between mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) and epilepsia partialis continua (EPC) in children. We report the case of a child presenting with numerous stroke-like episodes associated with EPC which, despite therapy, were not controlled and aggravated the clinical condition of our patient. We present the neuroradiological, biochemical, genetic and muscle biopsy findings, and EEG characteristics, with attention to polygraphic recordings which were done during wake and sleep periods. We consider the correlation with other possible etiological factors relating to EPC and in particular co-involvement of the basal ganglia as a cause of EPC in our patient.

Original languageEnglish
Pages (from-to)158-166
Number of pages9
JournalNeurophysiologie Clinique / Clinical Neurophysiology
Issue number3
Publication statusPublished - 1995


  • partial epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Neurology
  • Neuroscience(all)


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