Epilepsia partialis continua studied by PET

Marketa Hajek, Angelo Antonini, Klaus L. Leenders, Heinz Gregor Wieser

Research output: Contribution to journalArticle

Abstract

We report an [18F]fluordeoxyglucose (FDG)-PET study performed in an 11-year-old girl with a 5-month history of epilepsia partialis continua (epc). Visual inspection of PET images showed a hypermetabolic focus in the right central cortex and in the ipsilateral thalamus, which was confirmed by the absolute values of regional cerebral glucose metabolism (rCMRGlu). The thalamic hypermetabolism provides evidence for an involvement of thalamic nuclei in this ictally epileptic process. The scalp EEG revealed a theta-delta and sharp wave focus in the right Rolandic cortex at the same location as the hypermetabolic zone seen in PET. Simultaneously recorded EMG of the left tibialis anterior muscle showed regular jerks, time-locked to the sharp waves at the right central region, and myoclonic 'storms' during focal motor seizures. The results of the brain biopsy and the child's clinical course led us to a diagnosis of 'chronic encephalitis' of Rasmussen.

Original languageEnglish
Pages (from-to)44-48
Number of pages5
JournalEpilepsy Research
Volume9
Issue number1
DOIs
Publication statusPublished - 1991

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Keywords

  • 'Chronic encephalitis' of Rasmussen
  • Epilepsia partialis continua
  • [F]Fluordeoxyglucose (FDG)-PET

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology

Cite this

Hajek, M., Antonini, A., Leenders, K. L., & Wieser, H. G. (1991). Epilepsia partialis continua studied by PET. Epilepsy Research, 9(1), 44-48. https://doi.org/10.1016/0920-1211(91)90045-H