Pervasive developmental disorder not otherwise specified (PDD-NOS) is a frequent type of pervasive developmental disorder We studied epilepsy recurrence and features in 77 patients with PDD-NOS and 77 with autistic disorder (AD) matched for sex and age. Seizures recurred in 35.1% of PDD-NOS cases and in 20.8% of AD (p > 0.05). In PDD-NOS mild mental retardation prevailed (p <0.01) as positive neurological examination (p <0.05), cerebral lesions (p <0.01), EEG background abnormalities (p <0.001), rare genetic diseases (p <0.01). Familial antecedents for epilepsy prevailed in patients with PDD-NOS and seizures (p <0.01), psychomotor retardation in cases with seizures and/or EEG paroxysmal abnormalities (p <0.05). The association of different types of EEG paroxysmal abnormalities prevailed in PDD-NOS with epilepsy (p <0.05). The age of seizure onset was earlier in PDD-NOS than in DA (p <0.00000001). Our data suggest to perform a protocol of investigations for etiological diagnosis in PDD-NOS.
|Translated title of the contribution||Epilepsy in pervasive developmental disorder not otherwise specified|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Jul 2004|
ASJC Scopus subject areas
- Clinical Neurology