Abstract
A 45-year-old female migraineur with a long-standing history of drug-induced headache is described. She had been abusing caffeine (250 mg/day) and aspirin (5 gr/day). On the third day after discontinuation a withdrawal syndrome characterized by headache and a generalized tonic-clonic seizure occurred. The temporal association makes it likely that the convulsion episode is an integral component of the withdrawal syndrome in this patient. This extra feature of the withdrawal syndrome has never been described after caffeine and/or aspirin interruption. Possible pathogenetic mechanisms are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 333-337 |
| Number of pages | 5 |
| Journal | Functional Neurology |
| Volume | 11 |
| Issue number | 6 |
| Publication status | Published - Nov 1996 |
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Keywords
- aspirin
- caffeine
- headache
- seizures
- withdrawal
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Epileptic seizure during aspirin and caffeine withdrawal in a drug induced headache. / Antonaci, Fabio; Sances, Grazia; Manni, Raffaele; Buzzi, Maria Gabriella.
In: Functional Neurology, Vol. 11, No. 6, 11.1996, p. 333-337.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Epileptic seizure during aspirin and caffeine withdrawal in a drug induced headache
AU - Antonaci, Fabio
AU - Sances, Grazia
AU - Manni, Raffaele
AU - Buzzi, Maria Gabriella
PY - 1996/11
Y1 - 1996/11
N2 - A 45-year-old female migraineur with a long-standing history of drug-induced headache is described. She had been abusing caffeine (250 mg/day) and aspirin (5 gr/day). On the third day after discontinuation a withdrawal syndrome characterized by headache and a generalized tonic-clonic seizure occurred. The temporal association makes it likely that the convulsion episode is an integral component of the withdrawal syndrome in this patient. This extra feature of the withdrawal syndrome has never been described after caffeine and/or aspirin interruption. Possible pathogenetic mechanisms are discussed.
AB - A 45-year-old female migraineur with a long-standing history of drug-induced headache is described. She had been abusing caffeine (250 mg/day) and aspirin (5 gr/day). On the third day after discontinuation a withdrawal syndrome characterized by headache and a generalized tonic-clonic seizure occurred. The temporal association makes it likely that the convulsion episode is an integral component of the withdrawal syndrome in this patient. This extra feature of the withdrawal syndrome has never been described after caffeine and/or aspirin interruption. Possible pathogenetic mechanisms are discussed.
KW - aspirin
KW - caffeine
KW - headache
KW - seizures
KW - withdrawal
UR - http://www.scopus.com/inward/record.url?scp=0030424711&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030424711&partnerID=8YFLogxK
M3 - Article
VL - 11
SP - 333
EP - 337
JO - Functional Neurology
JF - Functional Neurology
SN - 0393-5264
IS - 6
ER -