Epithelial alterations adjacent to 111 vulvar carcinomas

G. Borgno, L. Micheletti, M. Barbero, M. Preti, L. Cavanna, B. Ghiringhello

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Abstract

Material from 111 invasive primary vulvar carcinomas was reviewed in order to study the histopathologic changes adjacent to the neoplasia. The histopathologic characteristics of the adjacent tissue were divided into categories. Dystrophic lesions were adjacent to invasive cancer in 57.6% of the cases, carcinoma in situ (CIS) in 21.6% and epithelial changes suggestive of human papillomavirus infection in 18.9%. A spectrum of epithelial changes, ranging from hyperplastic dystrophy without atypia to CIS, was found adjacent to nine cases of invasive carcinoma (8.1%). In 40.5% of the vulvar carcinomas there were no specific alterations surrounding the neoplasia. These data show that dystrophies and CIS were adjacent to invasive carcinomas in nearly 60% and 20% of cases, respectively.

Original languageEnglish
Pages (from-to)500-502
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume33
Issue number6
Publication statusPublished - 1988

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ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Borgno, G., Micheletti, L., Barbero, M., Preti, M., Cavanna, L., & Ghiringhello, B. (1988). Epithelial alterations adjacent to 111 vulvar carcinomas. Journal of Reproductive Medicine for the Obstetrician and Gynecologist, 33(6), 500-502.