Epstein-barr virus-associated nasopharyngeal carcinoma and local polymorphic B-cell lymphoproliferative disorder in a patient with HIV disease

Roberto Manfredi, Sergio Sabbatani, Umberto Gianelli, Ginevra Marinacci

Research output: Contribution to journalArticle

Abstract

A rare case report of HIV-associated nasopharyngeal carcinoma concurrent with local polymorphic B-cell lymphoproliferative disorder is reported and discussed on the ground of the most recent literature evidences. Only very few reports of nasopharyngeal carcinoma have been described until now in patients infected with HIV (one case in adults), and a coexisting lymphoid cell proliferation with a concurrent role of Epstein-Barr virus in prompting both disorders was never reported to date. The relevant pathogenetic, diagnostic, and therapeutic questions raised by this infrequent intriguing association retrieved in a patient with prominent HIV-related immunodeficiency are focused on.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalJournal of the International Association of Physicians in AIDS Care
Volume6
Issue number4
DOIs
Publication statusPublished - Dec 2007

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Keywords

  • diagnosis
  • Epstein-Bar virus
  • HIV
  • lymphoproliferative disorder
  • management
  • nasopharyngeal carcinoma
  • pathogenesis

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology
  • Dermatology

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