Epstein-Barr virus DNA in the cerebrospinal fluid of an HIV patient with primary cerebral lymphoma

A. Plebani, R. Pinzani, L. Vago, P. Cinque, F. Triulzi, F. Zibordi, L. Angelini

Research output: Contribution to journalArticle

Abstract

The case of a 7-month-old boy with vertically acquired immunodeficiency syndrome and multifocal primary cerebral lymphoma is reported. Neither neurological nor neuroradiological findings contributed towards the appropriate diagnosis. Positive Epstein-Barr virus DNA, assessed by means of polymerase chain reaction in cerebrospinal fluid, strongly suggested a diagnosis of primary cerebral lymphoma, which was subsequently confirmed by autopsy. Conclusion. The detection of Epstein Barr virus DNA using the polymerase chain reaction in cereospinal fluid is useful for the diagnosis of primary cerebral lymphoma.

Original languageEnglish
Pages (from-to)291-293
Number of pages3
JournalEuropean Journal of Pediatrics
Volume157
Issue number4
DOIs
Publication statusPublished - 1998

Keywords

  • Epstein-Barr virus DNA
  • Human immunodeficiency virus
  • Polymerase chain reaction
  • Primary cerebral lymphoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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