Abstract
The case of a 7-month-old boy with vertically acquired immunodeficiency syndrome and multifocal primary cerebral lymphoma is reported. Neither neurological nor neuroradiological findings contributed towards the appropriate diagnosis. Positive Epstein-Barr virus DNA, assessed by means of polymerase chain reaction in cerebrospinal fluid, strongly suggested a diagnosis of primary cerebral lymphoma, which was subsequently confirmed by autopsy. Conclusion. The detection of Epstein Barr virus DNA using the polymerase chain reaction in cereospinal fluid is useful for the diagnosis of primary cerebral lymphoma.
| Original language | English |
|---|---|
| Pages (from-to) | 291-293 |
| Number of pages | 3 |
| Journal | European Journal of Pediatrics |
| Volume | 157 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1998 |
Keywords
- Epstein-Barr virus DNA
- Human immunodeficiency virus
- Polymerase chain reaction
- Primary cerebral lymphoma
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Cite this
Plebani, A., Pinzani, R., Vago, L., Cinque, P., Triulzi, F., Zibordi, F., & Angelini, L. (1998). Epstein-Barr virus DNA in the cerebrospinal fluid of an HIV patient with primary cerebral lymphoma. European Journal of Pediatrics, 157(4), 291-293. https://doi.org/10.1007/s004310050813