TY - JOUR
T1 - Epstein-Barr virus DNA in the cerebrospinal fluid of an HIV patient with primary cerebral lymphoma
AU - Plebani, A.
AU - Pinzani, R.
AU - Vago, L.
AU - Cinque, P.
AU - Triulzi, F.
AU - Zibordi, F.
AU - Angelini, L.
PY - 1998
Y1 - 1998
N2 - The case of a 7-month-old boy with vertically acquired immunodeficiency syndrome and multifocal primary cerebral lymphoma is reported. Neither neurological nor neuroradiological findings contributed towards the appropriate diagnosis. Positive Epstein-Barr virus DNA, assessed by means of polymerase chain reaction in cerebrospinal fluid, strongly suggested a diagnosis of primary cerebral lymphoma, which was subsequently confirmed by autopsy. Conclusion. The detection of Epstein Barr virus DNA using the polymerase chain reaction in cereospinal fluid is useful for the diagnosis of primary cerebral lymphoma.
AB - The case of a 7-month-old boy with vertically acquired immunodeficiency syndrome and multifocal primary cerebral lymphoma is reported. Neither neurological nor neuroradiological findings contributed towards the appropriate diagnosis. Positive Epstein-Barr virus DNA, assessed by means of polymerase chain reaction in cerebrospinal fluid, strongly suggested a diagnosis of primary cerebral lymphoma, which was subsequently confirmed by autopsy. Conclusion. The detection of Epstein Barr virus DNA using the polymerase chain reaction in cereospinal fluid is useful for the diagnosis of primary cerebral lymphoma.
KW - Epstein-Barr virus DNA
KW - Human immunodeficiency virus
KW - Polymerase chain reaction
KW - Primary cerebral lymphoma
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U2 - 10.1007/s004310050813
DO - 10.1007/s004310050813
M3 - Article
C2 - 9578963
AN - SCOPUS:0031954922
VL - 157
SP - 291
EP - 293
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
SN - 0340-6199
IS - 4
ER -