Abstract
Epidemiologie and clinico-pathologie features of Hodgkin's disease suggest that an infectious agent may be involved in the pathogenesis of this puzzling disorder. Recently accumulated data provide direct evidence supporting a causal role of Epstein-Barr virus in a significant proportion of cases. In addition to allowing a better understanding of the complex pathogenesis of Hodgkin's disease, these virological advances, briefly reviewed herein, also constitute an important basis for the development of new therapeutic strategies.
| Original language | English |
|---|---|
| Pages (from-to) | 13-25 |
| Number of pages | 13 |
| Journal | Biomedicine and Pharmacotherapy |
| Volume | 52 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1998 |
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Keywords
- Epstein-Barr virus
- Hodgkin's disease
- Lymphomagenesis
ASJC Scopus subject areas
- Pharmacology
Cite this
Epstein-Barr virus in the pathogenesis of Hodgkin's disease. / Dolcetti, R.; Boiocchi, M.
In: Biomedicine and Pharmacotherapy, Vol. 52, No. 1, 1998, p. 13-25.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Epstein-Barr virus in the pathogenesis of Hodgkin's disease
AU - Dolcetti, R.
AU - Boiocchi, M.
PY - 1998
Y1 - 1998
N2 - Epidemiologie and clinico-pathologie features of Hodgkin's disease suggest that an infectious agent may be involved in the pathogenesis of this puzzling disorder. Recently accumulated data provide direct evidence supporting a causal role of Epstein-Barr virus in a significant proportion of cases. In addition to allowing a better understanding of the complex pathogenesis of Hodgkin's disease, these virological advances, briefly reviewed herein, also constitute an important basis for the development of new therapeutic strategies.
AB - Epidemiologie and clinico-pathologie features of Hodgkin's disease suggest that an infectious agent may be involved in the pathogenesis of this puzzling disorder. Recently accumulated data provide direct evidence supporting a causal role of Epstein-Barr virus in a significant proportion of cases. In addition to allowing a better understanding of the complex pathogenesis of Hodgkin's disease, these virological advances, briefly reviewed herein, also constitute an important basis for the development of new therapeutic strategies.
KW - Epstein-Barr virus
KW - Hodgkin's disease
KW - Lymphomagenesis
UR - http://www.scopus.com/inward/record.url?scp=0031908038&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031908038&partnerID=8YFLogxK
U2 - 10.1016/S0753-3322(97)86237-3
DO - 10.1016/S0753-3322(97)86237-3
M3 - Article
C2 - 9755791
AN - SCOPUS:0031908038
VL - 52
SP - 13
EP - 25
JO - Biomedicine and Pharmacotherapy
JF - Biomedicine and Pharmacotherapy
SN - 0753-3322
IS - 1
ER -