Epstein-Barr virus infection and chronic lymphocytic leukemia: A possible progression factor?

Riccardo Dolcetti, Antonino Carbone

Research output: Contribution to journalArticlepeer-review

Abstract

Epstein-Barr virus is pathogenically associated with a well defined group of lymphoid and epithelial tumors in which the virus directly drives transformation of infected cells. Recent evidence however indicates that this virus may infect a subpopulation of tumor cells in patients with chronic lymphocytic leukemia (CLL) and EBV infection has been also associated with Richter transformation in a fraction of cases. We herein review available data suggesting a possible role of EBV as a direct or micro-environmental progression factor in a subset of CLL.

Original languageEnglish
Article number22
JournalInfectious Agents and Cancer
Volume5
Issue number1
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Infectious Diseases
  • Oncology
  • Epidemiology
  • Cancer Research

Fingerprint Dive into the research topics of 'Epstein-Barr virus infection and chronic lymphocytic leukemia: A possible progression factor?'. Together they form a unique fingerprint.

Cite this