Epstein-Barr virus infection and chronic lymphocytic leukemia: A possible progression factor?

Riccardo Dolcetti; Antonino Carbone

doi:10.1186/1750-9378-5-22

Epstein-Barr virus infection and chronic lymphocytic leukemia: A possible progression factor?

Riccardo Dolcetti, Antonino Carbone

Centro di Riferimento Oncologico

Research output: Contribution to journal › Article › peer-review

Abstract

Epstein-Barr virus is pathogenically associated with a well defined group of lymphoid and epithelial tumors in which the virus directly drives transformation of infected cells. Recent evidence however indicates that this virus may infect a subpopulation of tumor cells in patients with chronic lymphocytic leukemia (CLL) and EBV infection has been also associated with Richter transformation in a fraction of cases. We herein review available data suggesting a possible role of EBV as a direct or micro-environmental progression factor in a subset of CLL.

Original language	English
Article number	22
Journal	Infectious Agents and Cancer
Volume	5
Issue number	1
DOIs	https://doi.org/10.1186/1750-9378-5-22
Publication status	Published - 2010

ASJC Scopus subject areas

Infectious Diseases
Oncology
Epidemiology
Cancer Research

Access to Document

10.1186/1750-9378-5-22

Fingerprint Dive into the research topics of 'Epstein-Barr virus infection and chronic lymphocytic leukemia: A possible progression factor?'. Together they form a unique fingerprint.

Cite this

@article{e2ce12f94be34289b58d3fe090f867e0,

title = "Epstein-Barr virus infection and chronic lymphocytic leukemia: A possible progression factor?",

abstract = "Epstein-Barr virus is pathogenically associated with a well defined group of lymphoid and epithelial tumors in which the virus directly drives transformation of infected cells. Recent evidence however indicates that this virus may infect a subpopulation of tumor cells in patients with chronic lymphocytic leukemia (CLL) and EBV infection has been also associated with Richter transformation in a fraction of cases. We herein review available data suggesting a possible role of EBV as a direct or micro-environmental progression factor in a subset of CLL.",

author = "Riccardo Dolcetti and Antonino Carbone",

year = "2010",

doi = "10.1186/1750-9378-5-22",

language = "English",

volume = "5",

journal = "Infectious Agents and Cancer",

issn = "1750-9378",

publisher = "BioMed Central",

number = "1",

}

TY - JOUR

T1 - Epstein-Barr virus infection and chronic lymphocytic leukemia

T2 - A possible progression factor?

AU - Dolcetti, Riccardo

AU - Carbone, Antonino

PY - 2010

Y1 - 2010

N2 - Epstein-Barr virus is pathogenically associated with a well defined group of lymphoid and epithelial tumors in which the virus directly drives transformation of infected cells. Recent evidence however indicates that this virus may infect a subpopulation of tumor cells in patients with chronic lymphocytic leukemia (CLL) and EBV infection has been also associated with Richter transformation in a fraction of cases. We herein review available data suggesting a possible role of EBV as a direct or micro-environmental progression factor in a subset of CLL.

AB - Epstein-Barr virus is pathogenically associated with a well defined group of lymphoid and epithelial tumors in which the virus directly drives transformation of infected cells. Recent evidence however indicates that this virus may infect a subpopulation of tumor cells in patients with chronic lymphocytic leukemia (CLL) and EBV infection has been also associated with Richter transformation in a fraction of cases. We herein review available data suggesting a possible role of EBV as a direct or micro-environmental progression factor in a subset of CLL.

UR - http://www.scopus.com/inward/record.url?scp=78549290718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78549290718&partnerID=8YFLogxK

U2 - 10.1186/1750-9378-5-22

DO - 10.1186/1750-9378-5-22

M3 - Article

C2 - 21092169

AN - SCOPUS:78549290718

VL - 5

JO - Infectious Agents and Cancer

JF - Infectious Agents and Cancer

SN - 1750-9378

IS - 1

M1 - 22

ER -