Abstract
Epstein-Barr virus is pathogenically associated with a well defined group of lymphoid and epithelial tumors in which the virus directly drives transformation of infected cells. Recent evidence however indicates that this virus may infect a subpopulation of tumor cells in patients with chronic lymphocytic leukemia (CLL) and EBV infection has been also associated with Richter transformation in a fraction of cases. We herein review available data suggesting a possible role of EBV as a direct or micro-environmental progression factor in a subset of CLL.
| Original language | English |
|---|---|
| Article number | 22 |
| Journal | Infectious Agents and Cancer |
| Volume | 5 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2010 |
ASJC Scopus subject areas
- Infectious Diseases
- Oncology
- Epidemiology
- Cancer Research