TY - JOUR
T1 - ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension
AU - Grünig, Ekkehard
AU - Eichstaedt, Christina
AU - Barberà, Joan-Albert
AU - Benjamin, Nicola
AU - Blanco, Isabel
AU - Bossone, Eduardo
AU - Cittadini, Antonio
AU - Coghlan, Gerry
AU - Corris, Paul
AU - D'Alto, Michele
AU - D'Andrea, Antonello
AU - Delcroix, Marion
AU - de Man, Frances
AU - Gaine, Sean
AU - Ghio, Stefano
AU - Gibbs, Simon
AU - Gumbiene, Lina
AU - Howard, Luke S
AU - Johnson, Martin
AU - Jurevičienė, Elena
AU - Kiely, David G
AU - Kovacs, Gabor
AU - MacKenzie, Alison
AU - Marra, Alberto M
AU - McCaffrey, Noel
AU - McCaughey, Paul
AU - Naeije, Robert
AU - Olschewski, Horst
AU - Pepke-Zaba, Joanna
AU - Reis, Abílio
AU - Santos, Mário
AU - Saxer, Stéphanie
AU - Tulloh, Robert M
AU - Ulrich, Silvia
AU - Noordegraaf, Anton Vonk
AU - Peacock, Andrew J
N1 - Copyright ©ERS 2018.
PY - 2018/12/21
Y1 - 2018/12/21
N2 - Objectives of this ERS Task Force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the Task Force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiologic mechanisms.In studies with 784 PH patients in total, including 6 randomised controlled trials, 3 controlled trials, 10 prospective cohort studies, and 4 meta-analyses exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from health care institutions, commissioners of health care and research funding institutions are of high need. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.
AB - Objectives of this ERS Task Force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the Task Force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiologic mechanisms.In studies with 784 PH patients in total, including 6 randomised controlled trials, 3 controlled trials, 10 prospective cohort studies, and 4 meta-analyses exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from health care institutions, commissioners of health care and research funding institutions are of high need. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.
U2 - 10.1183/13993003.00332-2018
DO - 10.1183/13993003.00332-2018
M3 - Article
C2 - 30578391
JO - European Respiratory Journal
JF - European Respiratory Journal
SN - 0903-1936
ER -