Eruptive syringomas with calcium deposits in a young woman with Down's syndrome

Carmelo Schepis, V. Torre, M. Siragusa, F. Albiero, R. Cicciarello, M. E. Gagliardi, V. Cavallari

Research output: Contribution to journalArticlepeer-review

Abstract

Eruptive syringomas are uncommon in the general population. We describe here an 18-year-old female, affected by Down's syndrome, who presented with an abrupt eruption of small skin-colored or reddish papules on the face, neck and limbs. Light microscopy allowed us to diagnose syringomas, whereas the study of the ultrastructural features revealed calcium deposits in many lumina and also in the mitochondria. This observation confirms the hypothesis that the syringeal structure plays a role in the pathogenesis of calcinosis cutis.

Original languageEnglish
Pages (from-to)345-347
Number of pages3
JournalDermatology
Volume203
Issue number4
DOIs
Publication statusPublished - 2001

Keywords

  • Calcinosis cutis
  • Down's syndrome
  • Syringoma

ASJC Scopus subject areas

  • Dermatology

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