Erythema multiforme-like manifestations and arthritis in a 3-year-old child with leukocytoclastic vasculitis

M. Gattorno, P. Picco, C. Gambini, A. Buoncompagni, E. Castagnola, V. Pistoia, C. Borrone

Research output: Contribution to journalArticlepeer-review

Abstract

A 3-year-old boy with erythema multiforme-like manifestations and severe articular involvement is reported. Because of the unusual onset of the cutaneous lesion a skin biopsy was performed, revealing the typical features of a leukocytoclastic vasculitis. A direct immunofluorescent study revealed C3 and IgM deposition within the wall and around the small vessels. The clinical and immunopathological findings in this patient were similar to those reported for the acute hemorrhagic edema of infancy (AHE) described in children younger than 2 years of age. The present case supports the hypothesis that AHE is a distinctive leukocytoclastic vasculitis of childhood, irrespective of the age at onset.

Original languageEnglish
Pages (from-to)329-332
Number of pages4
JournalClinical and Experimental Rheumatology
Volume15
Issue number3
Publication statusPublished - May 1997

Keywords

  • Childhood vasculitis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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