Erythema nodosum: A presenting sign of early onset sarcoidosis

C. Cancrini, F. Angelini, M. Colavita, E. Cortis, L. Chini, F. Mammone, P. Rossi, R. De Sanctis

Research output: Contribution to journalArticlepeer-review


'Early onset sarcoidosis' is a chronic granulomatous disease occurring in children younger than 5 years of age, and characterized by a classic symptom triad consisting of skin, eye and joint lesions, with on rare occasion pulmonary involvement. The disorder often goes unrecognized because of its rarity and, since polyarthritis and uveitis are the predominant symptoms, most of these children are misdiagnosed as having juvenile chronic arthritis (JCA). A child with erythema nodosum at 7 months of age, later diagnosed as JCA and definitively recognized as 'early onset sarcoidosis' is reported. This case shows that, whenever possible, a biopsy showing the typical picture of sarcoid granulomas is crucial to distinguish these clinical conditions.

Original languageEnglish
Pages (from-to)337-339
Number of pages3
JournalClinical and Experimental Rheumatology
Issue number3
Publication statusPublished - 1998


  • Early onset sarcoidosis
  • Erythema nodosum
  • Juvenile chronic arthritis
  • Uveitis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology


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