Abstract
Erythrocyte Na+/Li+ countertransport activity was investigated in 11 controls and 22 recent onset type I (insulin-dependent) diabetic patients with normal and high glomerular filtration rates. No differences in were observed in hyperfiltering compared to normofiltering patients or controls. The Na+/Li+ activity was correlated with blood glucose levels in insulin-dependent diabetics showing good glycemic control. Total cholesterol and triglyceride concentrations were similar among the three groups. In conclusion, enhanced Na+/Li+ countertransport activity is not associated, in our case, with diabetic condition per se and with early glomerular hyperfiltration and cannot be used as a marker of renal involvement in recent onset insulin-dependent diabetics. Am J Hypertens 1993;6:534-537.
| Original language | English |
|---|---|
| Pages (from-to) | 5345-5537 |
| Number of pages | 193 |
| Journal | American Journal of Hypertension |
| Volume | 6 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1993 |
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Keywords
- Glomerular hyperfiltration
- Na+/Li+ countertransport
- Type 1 diabetes
ASJC Scopus subject areas
- Internal Medicine
Cite this
Erythrocyte na+/li+ countertransport and glomerular hyperfiltration in insulin-dependent diabetics. / Rota, Rossella; Timsit, José; Hannedouche, Thierry; Ikeni, Aschour; Boitarc, Christian; Guicheney, Pascale.
In: American Journal of Hypertension, Vol. 6, No. 6, 1993, p. 5345-5537.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Erythrocyte na+/li+ countertransport and glomerular hyperfiltration in insulin-dependent diabetics
AU - Rota, Rossella
AU - Timsit, José
AU - Hannedouche, Thierry
AU - Ikeni, Aschour
AU - Boitarc, Christian
AU - Guicheney, Pascale
PY - 1993
Y1 - 1993
N2 - Erythrocyte Na+/Li+ countertransport activity was investigated in 11 controls and 22 recent onset type I (insulin-dependent) diabetic patients with normal and high glomerular filtration rates. No differences in were observed in hyperfiltering compared to normofiltering patients or controls. The Na+/Li+ activity was correlated with blood glucose levels in insulin-dependent diabetics showing good glycemic control. Total cholesterol and triglyceride concentrations were similar among the three groups. In conclusion, enhanced Na+/Li+ countertransport activity is not associated, in our case, with diabetic condition per se and with early glomerular hyperfiltration and cannot be used as a marker of renal involvement in recent onset insulin-dependent diabetics. Am J Hypertens 1993;6:534-537.
AB - Erythrocyte Na+/Li+ countertransport activity was investigated in 11 controls and 22 recent onset type I (insulin-dependent) diabetic patients with normal and high glomerular filtration rates. No differences in were observed in hyperfiltering compared to normofiltering patients or controls. The Na+/Li+ activity was correlated with blood glucose levels in insulin-dependent diabetics showing good glycemic control. Total cholesterol and triglyceride concentrations were similar among the three groups. In conclusion, enhanced Na+/Li+ countertransport activity is not associated, in our case, with diabetic condition per se and with early glomerular hyperfiltration and cannot be used as a marker of renal involvement in recent onset insulin-dependent diabetics. Am J Hypertens 1993;6:534-537.
KW - Glomerular hyperfiltration
KW - Na+/Li+ countertransport
KW - Type 1 diabetes
UR - http://www.scopus.com/inward/record.url?scp=84959756767&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959756767&partnerID=8YFLogxK
U2 - 10.1093/ajh/6.6.534
DO - 10.1093/ajh/6.6.534
M3 - Article
AN - SCOPUS:84959756767
VL - 6
SP - 5345
EP - 5537
JO - American Journal of Hypertension
JF - American Journal of Hypertension
SN - 0895-7061
IS - 6
ER -