In a prospective study of acute pharyngitis in Italian children, 69 (38.3%) of 180 isolates of Streptococcus pyogenes were resistant to macrolides. S. pyogenes was eradicated in 12 (63.1%) of 19 patients with erythromycin-resistant S. pyogenes treated with clarithromycin and in 22 (88%) of 25 patients with erythromycin-susceptible strains. The constitutive- resistant phenotype was correlated with failure of macrolide treatment.
|Number of pages||4|
|Journal||Emerging Infectious Diseases|
|Publication status||Published - Mar 2000|
ASJC Scopus subject areas
- Microbiology (medical)