Erythropoietin as an angiogenic factor

Domenico Ribatti, A. Vacca, A. M. Roccaro, E. Crivellato, M. Presta

Research output: Contribution to journalArticlepeer-review

Abstract

Erythropoietin (Epo) is produced by the fetal liver and adult kidney and is an essential stimulator of erythropoiesis. It has, however, been shown to modulate host cellular signal transduction pathway to perform many other functions. New sites of Epo production have been found, such as the female reproductive organs and central nervous system. This review summarizes the involvement of Epo in the regulation of angiogenesis in both normal and pathological conditions.

Original languageEnglish
Pages (from-to)891-896
Number of pages6
JournalEuropean Journal of Clinical Investigation
Volume33
Issue number10
DOIs
Publication statusPublished - Oct 1 2003

Keywords

  • Angiogenesis
  • Central nervous system
  • Erythropoietin
  • Hypoxia
  • Tumour

ASJC Scopus subject areas

  • Medicine(all)

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