Escalating doses of donor lymphocytes for incipient graft rejection following SCT for thalassemia

I. Frugnoli, B. Cappelli, R. Chiesa, E. Biral, A. Noè, C. Evangelio, M. Fossati, S. Napolitano, F. Ciceri, M. G. Roncarolo, S. Marktel

Research output: Contribution to journalArticlepeer-review

Abstract

Mixed chimerism (MC) and secondary graft failure are frequent events following SCT for thalassemia. There is limited information regarding the outcome of donor lymphocyte infusion (DLI) to prevent rejection, mainly from case reports describing only successful cases. We describe a series of seven children affected by β-thalassemia treated with escalating doses of DLI for level 2-3 MC (donor

Original languageEnglish
Pages (from-to)1047-1051
Number of pages5
JournalBone Marrow Transplantation
Volume45
Issue number6
DOIs
Publication statusPublished - Jun 2010

Keywords

  • donor lymphocytes infusion (DLI)
  • graft failure
  • mixed chimerism
  • rejection
  • thalassemia

ASJC Scopus subject areas

  • Hematology
  • Transplantation
  • Medicine(all)

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