Esophageal impedance/pH monitoring in pediatric patients: Preliminary experience with 50 cases

Girolamo Mattioli; Alessio Pini-Prato; Valerio Gentilino; Enrica Caponcelli; Stefano Avanzini; Stefano Parodi; Giovanni A. Rossi; Pietro Tuo; Paolo Gandullia; Claudio Vella; Vincenzo Jasonni

doi:10.1007/s10620-006-9374-z

Esophageal impedance/pH monitoring in pediatric patients: Preliminary experience with 50 cases

Girolamo Mattioli, Alessio Pini-Prato, Valerio Gentilino, Enrica Caponcelli, Stefano Avanzini, Stefano Parodi, Giovanni A. Rossi, Pietro Tuo, Paolo Gandullia, Claudio Vella, Vincenzo Jasonni

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

This paper describes multiple intraluminal impedance (MII) in 50 children with typical and atypical gastroesophageal reflux (GER) symptoms and discusses the possible clinical significance of objective numeric data provided by MII computed analysis. Patients underwent 24-hr pH/MII monitoring. Reflux parameters were analyzed with relation to age and reported symptoms. NonacidicMII events occurred as frequently as acidic ones. A Pathologic Bolus Exposure Index associated with a normal pH Reflux Index was detected in 26% of our series. Significant correlations were found regarding acid and bolus clearing times and their ratio. We conclude that the low rate of symptom occurrence in the pediatric population represents a limit on MII evaluation. Our study confirmed that nonacid GER is at least as frequent as acid GER. As MII provides interesting objective data that could be used in clinical practice, we suggest further research to define normal ranges in the pediatric population.

Original language	English
Pages (from-to)	2341-2347
Number of pages	7
Journal	Digestive Diseases and Sciences
Volume	51
Issue number	12
DOIs	https://doi.org/10.1007/s10620-006-9374-z
Publication status	Published - Dec 2006

Keywords

Atypical symptoms
Childhood
Gastroesophageal reflux
Impedance
PHmetry

ASJC Scopus subject areas

Gastroenterology
Physiology

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10.1007/s10620-006-9374-z

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Esophageal impedance/pH monitoring in pediatric patients : Preliminary experience with 50 cases. / Mattioli, Girolamo; Pini-Prato, Alessio; Gentilino, Valerio; Caponcelli, Enrica; Avanzini, Stefano; Parodi, Stefano; Rossi, Giovanni A.; Tuo, Pietro; Gandullia, Paolo; Vella, Claudio; Jasonni, Vincenzo.

In: Digestive Diseases and Sciences, Vol. 51, No. 12, 12.2006, p. 2341-2347.

Research output: Contribution to journal › Article › peer-review

Mattioli, Girolamo ; Pini-Prato, Alessio ; Gentilino, Valerio ; Caponcelli, Enrica ; Avanzini, Stefano ; Parodi, Stefano ; Rossi, Giovanni A. ; Tuo, Pietro ; Gandullia, Paolo ; Vella, Claudio ; Jasonni, Vincenzo. / Esophageal impedance/pH monitoring in pediatric patients : Preliminary experience with 50 cases. In: Digestive Diseases and Sciences. 2006 ; Vol. 51, No. 12. pp. 2341-2347.

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abstract = "This paper describes multiple intraluminal impedance (MII) in 50 children with typical and atypical gastroesophageal reflux (GER) symptoms and discusses the possible clinical significance of objective numeric data provided by MII computed analysis. Patients underwent 24-hr pH/MII monitoring. Reflux parameters were analyzed with relation to age and reported symptoms. NonacidicMII events occurred as frequently as acidic ones. A Pathologic Bolus Exposure Index associated with a normal pH Reflux Index was detected in 26% of our series. Significant correlations were found regarding acid and bolus clearing times and their ratio. We conclude that the low rate of symptom occurrence in the pediatric population represents a limit on MII evaluation. Our study confirmed that nonacid GER is at least as frequent as acid GER. As MII provides interesting objective data that could be used in clinical practice, we suggest further research to define normal ranges in the pediatric population.",

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author = "Girolamo Mattioli and Alessio Pini-Prato and Valerio Gentilino and Enrica Caponcelli and Stefano Avanzini and Stefano Parodi and Rossi, {Giovanni A.} and Pietro Tuo and Paolo Gandullia and Claudio Vella and Vincenzo Jasonni",

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AU - Avanzini, Stefano

AU - Parodi, Stefano

AU - Rossi, Giovanni A.

AU - Tuo, Pietro

AU - Gandullia, Paolo

AU - Vella, Claudio

AU - Jasonni, Vincenzo

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Esophageal impedance/pH monitoring in pediatric patients: Preliminary experience with 50 cases

Abstract

Keywords

ASJC Scopus subject areas

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