Esophageal impedance/pH monitoring in pediatric patients: Preliminary experience with 50 cases

Girolamo Mattioli, Alessio Pini-Prato, Valerio Gentilino, Enrica Caponcelli, Stefano Avanzini, Stefano Parodi, Giovanni A. Rossi, Pietro Tuo, Paolo Gandullia, Claudio Vella, Vincenzo Jasonni

Research output: Contribution to journalArticlepeer-review


This paper describes multiple intraluminal impedance (MII) in 50 children with typical and atypical gastroesophageal reflux (GER) symptoms and discusses the possible clinical significance of objective numeric data provided by MII computed analysis. Patients underwent 24-hr pH/MII monitoring. Reflux parameters were analyzed with relation to age and reported symptoms. NonacidicMII events occurred as frequently as acidic ones. A Pathologic Bolus Exposure Index associated with a normal pH Reflux Index was detected in 26% of our series. Significant correlations were found regarding acid and bolus clearing times and their ratio. We conclude that the low rate of symptom occurrence in the pediatric population represents a limit on MII evaluation. Our study confirmed that nonacid GER is at least as frequent as acid GER. As MII provides interesting objective data that could be used in clinical practice, we suggest further research to define normal ranges in the pediatric population.

Original languageEnglish
Pages (from-to)2341-2347
Number of pages7
JournalDigestive Diseases and Sciences
Issue number12
Publication statusPublished - Dec 2006


  • Atypical symptoms
  • Childhood
  • Gastroesophageal reflux
  • Impedance
  • PHmetry

ASJC Scopus subject areas

  • Gastroenterology
  • Physiology


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