Esophagogastric junction morphology is associated with a positive impedance-pH monitoring in patients with GERD

S. Tolone, C. De Cassan, N. De Bortoli, S. Roman, F. Galeazzi, R. Salvador, E. Marabotto, M. Furnari, P. Zentilin, S. Marchi, R. Bardini, G. C. Sturniolo, V. Savarino, Edoardo Savarino

Research output: Contribution to journalArticlepeer-review

Abstract

Background: High-resolution manometry (HRM) provides information on esophagogastric junction (EGJ) morphology, distinguishing three different subtypes. Data on the correlation between EGJ subtypes and impedance-pH detected reflux patterns are lacking. We aimed to correlate the EGJ subtypes with impedance-pH findings in patients with reflux symptoms. Methods: Consecutive patients with suspected gastroesophageal reflux disease (GERD) were enrolled. All patients underwent HRM and impedance-pH testing off-therapy. EGJ was classified as: Type I, no separation between the lower esophageal sphincter (LES) and crural diaphragm (CD); Type II, minimal separation (>1 and

Original languageEnglish
Pages (from-to)1175-1182
Number of pages8
JournalNeurogastroenterology and Motility
Volume27
Issue number8
DOIs
Publication statusPublished - Aug 1 2015

Keywords

  • Esophagogastric junction
  • GERD
  • High-resolution manometry
  • Impedance monitoring

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Gastroenterology
  • Physiology

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